Wednesday 28 February 2018

Revenue in Ultrasound Devices Market to Breach US$ 11.0 Bn Mark by 2023

According to a TMR analyst, “The global market for ultrasound devices is expected to witness a CAGR of 5.8% between 2015 and 2023. Rising from a valuation of US$6.7 bn in 2014, the market will most likely touch US$11 bn by the end of 2023.”

Doppler Technology to be Prospect of Ultrasound Devices

The high rate of mechanical headways happening presently are relied upon to cut the street for the eventual fate of ultrasound gadgets. One of the prime product advancements is the Doppler ultrasound gadget, and it is relied upon to pick up client support and market income share at a fast rate sooner rather than later. Doppler ultrasound gadgets are to a great degree profitable for imaging of blood stream and blood maladies. The symptomatic sharpness that Doppler ultrasound gadgets can add enables medicinal staff to rapidly focus on the issue and give successful treatment. Cutting edge concepts such as pocket ultrasound devices and Doppler ultrasound devices are anticipated to pave a successful path for sales in the near future.

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Region-wise, in 2014, the leading share of 33.8% in terms of revenue was accounted by Europe. It was closely trailed by Asia Pacific. However, the market is expected to witness a paradigm shift with Asia Pacific taking over the market giant Europe and replacing it to be the leading region in the global ultrasound devices market by the end of 2023. This sudden growth of the market in Asia Pacific can be attributed to the high amount of investments being made from China along with supportive healthcare reforms, thus increasing the adoption of ultrasound devices in the region.

Growing Patent Count to Accelerate Sales of Ultrasound Devices

"Most therapeutic administrative and counseling bodies, including the WHO, concur that the quantity of patients experiencing cardiovascular ailments is developing at an alarmingly high rate," expresses a TMR expert. "The WHO clarifies that the quantity of heart patients is relied upon to cross 23 mn by 2030. This is all that anyone could need to demonstrate that human services associations around the globe are in grave requirement for cutting edge ultrasound gadgets."

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Comparative conditions can be found on account of tuberculosis, as the WHO expressed that the rising populace thickness is making it less demanding for the illness to spread and contaminate more individuals. TB is another sickness that can be successfully determined to have ultrasound gadgets, additionally boosting its request. However, the market might face little hindrances owing to the difficulty associated with the operation of these devices. Thus, to make these devices handy and light weight, researchers are focusing on making them technologically advanced enough to suit everyone’s purpose.

The global ultrasound devices market is highly consolidated with few key players leading the market, states Transparency Market Research (TMR) in a research report. Koninklijke Philips N.V., Fujifilm Holdings, and GE Healthcare were the leading companies operating in the market in 2014. In the exact same year, they collectively held a share of 67.1% in terms of revenue. This proves the level of consolidation in the market is extremely high. The vast majority of the major worldwide and provincial players figure out how to secure strong ground in this market through long haul deals contracts with clients. New contestants to the ultrasound gadgets situation won't just need to go up against the mammoth piece of the overall industry held by these best players, additionally need to oversee stores amid the costly starting period of establishment and acquisition.

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Wearable Medical Devices Market is Expanding at a CAGR of 18.0% by 2023

The top five players in the wearable medical devices market accounted for a combined market share of 47.0% in 2014, which leads to some degree of consolidation in an otherwise fragmented market. Some of the leading companies are Polar Electro, Fitbit, Inc., OMRON Corporation, and Medtronic, with OMRON Corporation holding a significant revenue share of almost 11.0% in the same year. The global electronics company increasingly focuses on home healthcare devices, usually portable medical devices such as pedometers and blood pressure monitors to strengthen its shares. Another major player Fitbit, Inc., pioneers in offering wearable technology devices for tracking fitness to gain a competitive edge over others.

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The presence of large number of regional players makes the wearable medical devices market intensely competitive. Several smaller players in the market strive to develop innovative products to get a strong foothold in the market, while large players are boosting their distribution chains to consolidate their markets shares across regions. The global wearable medical devices market was valued at US$2.7 bn in 2014 and the opportunities in the market is expected to reach about US$10 bn by 2023. The market is projected to rise at a robust CAGR of 18.0% from 2015 to 2023.

Increased Reliability and Portability Bolster Uptake of Wearable Electrocardiographs

Geographically, the global wearable medical devices market is segmented into North America, Europe, Asia Pacific, and Rest of the World. Of these, North America is the major regional market and is expected to reach a valuation of US$4.5 bn by the end of the forecast period. The substantial growth of this regional market is driven by the presence of large number of mid-sized and large companies, rapid emergence of new players, and early adopters.

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Based on diagnostic device, the wearable medical devices is segmented into neuromonitoring devices, vital signs monitors, and fetal monitors and obstetrics devices. The neuromonitoring devices is further sub-segmented into electroencephalograph and electromyography. The major sub-segments of vital signs monitors are heart rate monitor, sleep monitor, activity monitor, and electrocardiograph. The electrocardiograph segment is projected to grow at a significant CAGR of 17.8% during the forecast period, primarily attributed to growing prevalence of cardiovascular diseases.

Real-Time Monitoring of Health Conditions Boost Demand

The global wearable medical devices is primarily driven by the rapidly growing demand for these devices for health monitoring and in the diagnosis of various diseases. Constant product innovations is a key factor boosting the market. The burgeoning demand of portable and high-end devices to monitor fitness among athletes and tech-savvy people is expected to fuel the wearable medical devices market. The growing prevalence world over and the increasing incidence of chronic diseases among geriatric population are anticipated to catalyze the market in the coming years. The need for real-time monitoring of medical conditions of outpatients suffering from chronic medical conditions is another crucial factor spurring the demand for wearable medical devices. In addition, the advent of cost-effective wearable medical devices that provide basic functionalities such as monitoring glucose levels and blood pressure among ailing people is expected to boost the market through the forecast period.

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The use of wearable medical devices for real-time monitoring of health conditions by clinicians is another seminal factor bolstering the uptake of these devices. However, the vulnerabilities associated with hacks of wearable devices is a key concern likely to hinder the adoption to an extent. Be that as it may, several governmental regulations, such as the EU regulations, ensuring the safety and performance of medical wearable is expected to bode well for the market in the coming years. In addition, major collaborations between technology companies and medical device manufacturers are expected to create exciting opportunities for market players.

Teleradiology Market is Expanding at a CAGR of 11.3% by 2023

The highly fragmented market for teleradiology features the presence of a large number of regional players, with the exception of some large companies with international presence, such as vRad, Inc., Radiology Reporting Online, and USA Rad. North America and Europe, the regions with some of the largest vendors in the global teleradiology market, will be the key enablers of teleradiology practices across the world and play a central role in the overall development of the global market, notes a recent report by Transparency Market Research (TMR).

Acquisitions of small, regional players, and long-term contracts with remotely located community hospitals and other healthcare service providers, especially across emerging markets such as Asia Pacific and Latin America, will allow teleradiology companies to expand their global footprint. Although less in number than in the European market, teleradiology companies in North America will contribute the largest share in the overall revenues of the global teleradiology market from 2015 through 2023, thanks to their global presence.

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Rise in Healthcare Expenditure and Improved Healthcare Infrastructure to Enable Widespread Adoption of Teleradiology

The vast improvement in telecommunication networks, enhanced data transfer speeds, and improved digital infrastructure of remote parts of the world has revolutionized the global teleradiology market in the past few years. In the next few years as well, developments across the data transmission field will be prove to be a major driver of the global teleradiology market, allowing its evolution from an ancillary radiology discipline to a mainstream practice.

Radiology is a cost-intensive diagnostic modality owing to the high prices of the technologically advanced medical imaging machines central to the field. This factor, in combination with the factor of unavailability of broadband networks in urban dwellings has remained one of the toughest challenges for the teleradiology market in the past years. However, substantial rise in healthcare expenditures and widened broadband networks in the past few years have enabled the widespread expansion of teleradiology practices on a global front. These factors have especially allowed the teleradiology market in extending its reach to emerging economies such as Latin America and Asia Pacific, considered to be the regional markets with the most lucrative growth opportunities.

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Asia Pacific to Provide Most Attractive Growth Opportunities

North America is currently the leading regional market for teleradiology and is expected to provide considerable growth opportunities over the next few years as well. The market in the region will be driven by the digitally advanced healthcare infrastructures, integration of teleradiology services in the workflow of a vast number of medical imaging service providers, and high healthcare awareness among the population. The rising prevalence of a number of cancers in the region has also led to an increased need for effective teleradiology services in the region.

Nevertheless, Asia Pacific will provide the most lucrative growth opportunities for the global teleradiology market in the coming years. Factors fueling demand for teleradiology services in the region will be the rising expenditure on health and wellbeing, improving healthcare infrastructure, and widening network of high-speed broadband services.

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The global teleradiology market is expected to expand at a favorable 11.3% CAGR over the period between 2015 and 2023, and rise from a valuation of US$1,354.6 mn in 2014 to US$3,632.6 mn in 2023.

Active Pharmaceutical Ingredients (API) Market is Expanding at a CAGR of 6.3% by 2023

The frontrunners in the global active pharmaceutical ingredients (API) market in 2015, according to a study by Transparency Market Research (TMR), were North China Pharmaceutical Group Corp. (NCPC), Zhejiang Medicine Co. Ltd and Zhejiang NHU Co. Ltd., Teva Pharmaceutical Industries Ltd., and Northeast Pharmaceutical Group Co. Ltd. Key players are banking on strategic mergers and acquisitions to expand their presence across different geographies. Besides this, players are also focusing towards research and development activities to deliver result-oriented drugs. “The global API market features high entry and exit barriers owing to the large capital investment requirement for set-up,” says TMR’s lead analyst.

The opportunity in the global active pharmaceutical market was pegged at US$134.7 bn in 2015 and is poised to rise to US$219.60 bn by 2023, progressing at a CAGR of 6.3% between 2015 and 2023.

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North America to Lead Revenue Generation through 2023

On the basis of therapeutic area, the global API market will be dominated by cardiovascular disorders throughout the forecast period. The segment is also expected to expand at a significant CAGR of 6.63% during the same period. Geographically, North America will be at the forefront of growth in terms of revenue until 2023. The domicile of some pharmaceutical giants and the advent of biosimilars is providing a competitive edge to North America over other regions. Emerging countries such as China, India, and South Korea will offer ample of lucrative growth opportunities to market players.

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Rising Penetration of Information Technology in Healthcare Sector to Bode Well for Growth of API Market

With exponentially rising demand for drugs, the global API market is expected to follow a notable growth trajectory during the forecast period. “Considering the rapidly growing global population, technological advancements, and widening pool of patients suffering from chronic diseases, the pace of development of drugs is likely to increase by leaps and bounds,” says a TMR analyst. The rising geriatric population worldwide is also escalating the demand for various types of drugs, which in turn working in favor of the global market.
Moreover, the improving access to healthcare in emerging countries coupled with the increasing penetration of information and communication technology in the healthcare sector is positively impacting the growth of the market. In addition, the increasing healthcare budgets in both developed and developing countries are also triggering the sales of API. Besides this, the increasing efforts by Indian API manufacturers to comply with the U.S. FDA norms are also stoking the growth of the overall market.

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Empowering Presence of Generic Drugs to Inhibit Adoption of API

The burgeoning sales of generic drugs are acting as a major bottleneck in the development of the global API market. The patent expiry along with the shortage of blockbuster drugs, poor accessibility in remote areas of several emerging countries, and unaffordability are fuelling the consumption of generic drugs. However, several government organizations are taking measures to mitigate this issue. The European Union (EU) are setting up manufacturing facilities that not only help in improving the quality of the drugs sold in the market, but also in ensuring the sales of government-approved and quality-checked scientifically-developed drugs. 

Asia Preimplantation Genetic Diagnosis Market to Surge at a CAGR of 6.8% by 2023

The Asia perimplantation genetic diagnosis market is anticipated to exhibit a 6.8% CAGR between 2015 and 2023. The market is expected to rise to a valuation of US$28.8 mn by the end of 2023 from worth US$16.0 mn in 2014.

Single Gene Disorder Screening to be Preferred over Prenatal Diagnostic Testing

Preimplantation hereditary finding for the screening of aneuploidy held the chief offer of 34.7% in the Asia PGD showcase in 2014. Liberal controls relating to this range of conclusion in most Asian nations is the central point behind the high quantities of aneuploidy screening tests embraced each year in the district. Be that as it may, PGD for single quality issue is anticipated to grow at the quicker CAGR from the period in the vicinity of 2015 and 2023. Expanded inclination of this demonstrative methodology is supported by innovative progressions and generally high precision of results. Additionally, single quality issue screening is more useful contrasted with customary pre-birth demonstrative testing in developing life, driving the market for PGD for single quality issue.

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Region-wise, the Asia preimplantation genetic diagnosis market is likely to witness fruitful opportunities in the Southern Asia region. In most Asian nations where PGD is not disallowed, it is controlled by the provincial or national government. The high expenses of PGD methods are likewise a zone of massive worry for certain cost sensitive nations in the area. Consolidated with liberal administrative standards and the rising populace of high-procuring people, Southern Asia will rise as the most lucrative market for preimplantation hereditary conclusion in the following couple of years. The PGD advertise in Southern Asia is required to ascend at an ideal 7.9% CAGR from 2015 to 2023.

Growing Penchant towards Assisted Reproductive Techniques to Bolster Deployment

Rising inclination to helped regenerative methods, which include preimplantation hereditary finding as a standard game-plan for guaranteeing that the incipient organism is free of any hereditary oddities, is integral to the solid development of the Asia PGD advertise. The interest for helped regenerative systems in the locale is driven significantly because of two elements: postponed period of origination among ladies and the alarmingly rising rate of fruitlessness in the area. With rising support in the locale's workforce, countless ladies are considering their infants in late 20s to late 30s. As infertility issues and difficulties worried about imagining begin heightening as the age rises, couples in the area are progressively favoring helped conceptive systems, for example, in vitro treatment.

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The rate of infertility in nations, for example, China and India has considerably expanded in the previous couple of years. Xinhua, one of China's unmistakable news offices has expressed that around 12.5% of China's populace was fruitless in 2010. In India as well, around 10% of the populace was said to be experiencing infertility in 2013. This factor is likely to be a core triggering factor for the growth of the market.

The competitive scenario in the Asia preimplantation genetic diagnostics market is highly intense owing to the several global and local players trying their luck in the region, states Transparency Market Research (TMR) in a research report. Pertaining to the number of service providers of preimplantation genetic diagnosis market, it is a highly fragmented one in nature. The penetration of other regional players might further intensify the level of competition in the market in the years ahead. Some of the companies operating in the market might be F. Hoffmann-La Roche, Thermo Fisher Scientific Inc., Perkin Elmer Inc., Illumina Inc., Natera Inc., and Abbott Laboratories, among many others.

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Tuesday 27 February 2018

Hepatic Encephalopathy Market Share and Growth Factors Impact Analysis 2017 - 2025

Hepatic encephalopathy is a disorder detected in patients suffering from cirrhosis. It is a syndrome that occurs in patients with liver dysfunction and is defined as a spectrum of neuropsychiatric abnormalities, after exclusion of brain disease. Hepatic encephalopathy is categorized by intellectual impairment, a depressed level of consciousness, and personality changes. The symptoms of hepatic encephalopathy includes changes in sleeping patterns, disorientation, slurred speech and agitation, drowsiness or confusion, and excitement. The influencing factors for hepatic encephalopathy includes constipation (due to increased nitrogen load), increased protein intake with azotemia, drugs, and hypoxia, gastrointestinal bleeding, and renal dysfunction.

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The hepatic encephalopathy market can be segmented by types, treatment, and geography. Based on types, the market can be categorized into Type A, Type B, and Type C. Type A hepatic encephalopathy is related to acute liver failure that leads to rapid deterioration of the liver in patients suffering from pre-existing liver disorders. Acute liver failure that causes complications such as elevated pressure and excessive bleeding in the brain is known as fulminant hepatic failure that requires emergency hospitalization. Type B hepatic encephalopathy is related to portal-systemic bypass deprived of liver disorder. Type B hepatic encephalopathy arises when blood streams around the liver and hence the liver cannot remove or control elements in the blood. Type B generally arises as a result of hereditary abnormalities and as a result of invasive procedures or trauma. Type C hepatic encephalopathy is related to cirrhosis. Cirrhosis is the last phase of chronic liver disease when damaging fibrosis matures. As a result, problems of cirrhosis is reflected in bruising and bleeding easily, jaundice (a yellow discoloration of the skin and whites of the eyes), painful swelling of the legs (edema), fluid build-up in the abdomen (ascites), and portal hypertension (a rise in the blood pressure within a system of veins called the portal venous system).

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Furthermore, on the basis of treatments, the hepatic encephalopathy market is categorized into lactulose, antibiotics, probiotics, branched-chain amino acids, and liver transplantation. Lactulose is a synthetic form of sugar that is not absorbed into the body. Lactulose creates an aggressive environment for the bad microbes in the intestine, thus reducing ammonia production in the intestine. Antibiotics such as Rifaximin and Metronidazole may be used to slow down the development of bacteria in the intestine, including bacteria which produce ammonia. Rifaximin is slowly absorbed into the body that helps it to deliberate in the intestines, where it can decrease the growth of unfavorable bacteria. Probiotics or favorable microbes can change the balance of microbes in the intestines, increasing the proportion of favorable bacteria. This can result in reduced levels of ammonia production and other toxic substances. Branched-chain amino acids Valine, Leucine, and Isoleucine can help uphold muscle mass and increase ammonia clearance. Liver transplantation is the final treatment for hepatic encephalopathy wherein the damaged liver is replaced with a healthy donor’s liver. Patients who receive a liver transplant recover their brain function. However, it is important to control and stop incidents of over hepatic encephalopathy, because several incidents of over hepatic encephalopathy can possibly lead to enduring and therefore irreversible brain damage.

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On the basis of geography, the global hepatic encephalopathy market is segmented into five key regions, North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is the dominant market followed by Europe. Rising patient awareness about different treatment options and increasing demand for treatment is expected to influence the market in North America. The hepatic encephalopathy market is growing due to increasing population, better treatment options, and rising demand for rapid diagnosis globally. Presently, the U.S. is the main country contributing to the global hepatic encephalopathy market, where the financial burden of hepatic encephalopathy is significant. Followed by ascites, hepatic encephalopathy is the second most common cause for hospitalization of cirrhotic patients in the U.S. In addition, the market for global hepatic encephalopathy is expected to expand at a healthy rate in the next few years due to lack of treatment options.

The major players operating in the global hepatic encephalopathy market are Alfa Wassermann S.p.A, Cosmo Pharmaceuticals S.p.A, KannaLife Sciences, Inc., Ocera Therapeutics, Inc., Rebiotix Inc., Spherium Biomed S.L., and Umecrine Cognition AB among others. Increasing competition among key players to develop new therapies for hepatic encephalopathy will drive the market globally.

Endoscope Reprocessors Market Share and Growth Factors Impact Analysis 2017 - 2025

The endoscope is an important therapeutic tool and diagnostic tool in the modern age. Endoscopy procedures are used for diagnosis, prevention, and treatment of the complications of internal organs. Endoscope reprocessors is used for sterilization, cleaning, and decontamination of an endoscopes. The physician uses the endoscope for a number of times to treat and diagnose various disease. The endoscope is used on various number of patients, once use, it is contaminated with micro-organism and it is very important to cleanse it and make it completely micro-organism free. To prevent transfer of disease endoscope must be sterile before use. Endoscopes are cleansed with special care and cleanse by a skilled and trained person. Proper methods and practices are performed to clean the endoscope. Design of endoscopes are in such a way that it is reprocessed properly and easily. Flexible endoscope carries a high level of micro - organism since they are used in several cavities of the body for treatment and diagnosis. Each endoscope has been a different type of sterilization and cleaning process, the instruction is on the label given by the manufacturer of the product. For use of endoscope reprocessors device and sterilization, disinfection, and cleaning of endoscope, one must follow the manufacturer’s instruction and various standard organization process to achieve the completely micro - organism free cleaning and to avoid the future problems.

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Global market has been classified on the basis of product type, modality, end users, and region. In term of product type, the endoscope reprocessors market is segmented into the ultrasonic washer, pasteurizer, washer-disinfector, sterilizer and automated endoscope reprocessor (AER). The automated endoscope reprocessor segment can be further segmented into a single basin automated endoscope reprocessor and dual basin automated endoscope reprocessor. Automated endoscope reprocessor segment is expected to grow in positive traction and success rate in cleaning endoscopes in the global endoscope reprocessors market. Based on the modality, the endoscope reprocessors market is segmented into the stand alone endoscopic reprocessor and table top endoscopic reprocessor. End users for the endoscope reprocessors market is the hospital, ambulatory surgical centers, and specialty clinics.

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Endoscope reprocessors market is anticipated to grow due to increase in the number of the endoscope operating procedures and also rise in the endoscope diagnosis procedures. Apart from this, increased awareness about disinfection and sterilization. Moreover, increase in geriatric population who are more prone to diseases and requires a regular medical check-ups, this positively affect endoscope reprocessors market during the forecast period 2017 to 2025. However, there are drawbacks in cleaning the endoscope such as chemical sensitive material or thermal sensitive material, professional and skilled person is needed to use the device to avoid future problems may hinder the growth of endoscope reprocessors market during the forecast period.

Geographically, endoscope reprocessors market is divided into five major regions viz. North America, Europe, Asia-Pacific, Latin America, and Middle East and Africa. North America and Europe will remain key markets for endoscope reprocessors market due to high number of the endoscopic surgical procedures and strong presence of big players in the market. Asia Pacific is tend to show a positive growth owing to large number of patient pool, aging population and increasing scope medical tourism. India, China, and Brazil are expected to fuel expansion of the market due to increasing investments by government bodies to enhance health care facilities.

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Key companies operating in the global endoscope reprocessors market are STERIS Plc., Getinge AB, Ecolab Inc., Olympus Corporation, ENDO-TECHNIK W.Griesat GmbH, Wassenburg Medical B.V., Steelco S.p.A., MEDIVATORS Inc. (Cantel Medical Corp.), HOYA Group and Johnson & Johnson.

Mitotic Inhibitors Market Share and Growth Factors Impact Analysis 2017 - 2025

Mitosis is a process of cell division, wherein a cell divides into an identical cell through multiplication and separation of its chromosomes. The separation of chromosomes is carried out by microtubules in the cell. Mitotic inhibitors are substances that inhibit the separation of chromosomes by binding to tubulin, which are the building blocks of microtubules. Mitotic inhibitors are naturally derived products from various plant extracts. Mitotic inhibitors are widely used in the life sciences and medical industries. Mitotic inhibitor drugs are used to treat various types of cancer using chemotherapy. These drugs are targeted at cancer cells to stop multiplication and help eradicate cancer.

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Mitotic inhibitors are widely used in life sciences for various studies such as study of chromosomes (cytogenetic). Several industry players are investing in the development and commercialization of mitotic inhibitor drugs to treat cancer and other medical conditions. Natural occurrence and efficiency in treating cancer are likely to increase the uptake of these drugs during the forecast period. Besides treating cancer, mitotic inhibitors have applications in antibiotics to control fungal infection and some are found to be useful in treating gout. Investments are being made to expand applications of mitotic inhibitors in the health care industry. However, several side effects are associated with the use of mitotic inhibitor drugs in cancer treatment, including nerve damage, muscle and joint pain, and nausea & vomiting. This in turn is anticipated to limit their use, thereby hampering market growth.

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The global mitotic inhibitors market can be segmented based on product type, application, end-user, and region. In terms of product type, the market can be divided into taxanes, vinca alkaloids, colchicine, podophyllotoxins, and others. The taxanes and vinca alkaloids segments are anticipated to account for significant shares of the global mitotic inhibitors market and are likely to experience strong growth during the forecast period from 2017 to 2025. Availability of large number of cancer drugs is expected to augment these segments. Based on application, the global mitotic inhibitors market can be segmented into therapeutics and life sciences. High consumption and high cost of therapeutic mitotic inhibitors are anticipated to drive the therapeutics segment during the forecast period. Based on end-user, the market can be classified into hospitals, ambulatory surgical centers, academic research institutes, and others.

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Geographically, the global mitotic inhibitors market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is expected to constitute a large share of the global market during the forecast period, owing to high consumption of these drugs for cancer treatment. Moreover, high usage of mitotic inhibitors in life sciences in this region is projected to fuel the growth of the mitotic inhibitors market in North America during the forecast period from 2017 to 2025. Europe is anticipated to account for a significant share of the global market during the forecast period. According to the World Health Organization, around 3.7 million new cancer cases are registered in Europe each year. Increase in health care expenditure in Asia Pacific is likely to propel the market during the forecast period. Furthermore, increasing investment in life sciences is projected to boost the growth of the mitotic inhibitors market in Asia Pacific.
Major players operating in the global mitotic inhibitors market are Teva Pharmaceutical Industries Ltd., Pfizer, Inc., Eisai Co., Ltd., Bristol-Myers Squibb Company, Celgene Corporation, Novartis AG, Pharm US LLC, Merck KGaA, AdooQ BioScience, and Enzo Life Sciences, Inc., among others.

Taxoplasmosis Encephalitis Market Share and Growth Factors Impact Analysis 2017 - 2025

Taxoplasmosis encephalitis is an infection caused by Taxoplasma gondii, an intracellular protozoan parasite. The infection can occur pre-natally or post-natally. It may be caused by exposure or consumption of undercooked meat, drinking of unpasteurized goat milk, contact with soil, cleaning of cat litter boxes, and ingestion of unwashed raw fruits or vegetables. The infection can also occur during organ transplantation or due to laboratory accidents. Prevalence of the infection varies from country to country. The prevalence is high in Latin America and countries of tropical Africa. North America, Southeast Asia, Northern Europe, and Africa witness low sero-prevalence, while Central and Southern Europe witness moderate prevalence of the disease.

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The global taxoplasmosis encephalitis market can be segmented based on diagnostic tests and geography. Diagnostic tests include serological investigations, direct detection, and imaging. Presence of IgG antibodies indicates risk of infection. Monitoring of IgM and IgA levels in neonates helps in screening of the infection. Imaging tests comprise MRI or CT scanning for brain lesions. Newer scanning procedures viz. PET or SPECT imaging assist in distinguishing taxoplasma encephalitis from other infections of the central nervous system. Fetal or neonatal ultrasonography can be performed in cases of known transplacental infection. Positron emission tomography (PET) or single-photon emission computed tomography (SPECT) scanning can be helpful in distinguishing between taxoplasmosis encephalitis and primary central nervous system (CNS) lymphoma. However, no imaging technique is completely specific.

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Polymerase chain reaction (PCR) amplification technique, screening of tissue sections or body smears, and tests such as tissue culture or biopsy stain are some of the direct tests for detecting the presence of Taxoplasma gondii. Tissue section and body smearing tests are conducted to find out the presence of tachyzoites, which is an active form of the parasite. Polymerase chain reactions allow detection of presence of the parasite in the blood, the body tissues, and the fluids. This test particularly helps in the diagnosis of disseminated disease, especially in HIV patients and intrauterine toxoplasmosis patients. Individuals infected with HIV should be tested for IgG antibody against the organism to detect the latent infection of T. gondii.

Patients with taxoplasmosis encephalitis are administered anticonvulsants if they have past history of seizures. However, it is not recommended as prophylaxis for all patients. Other drugs which may be administered to treat the infection are pyrimethamine, sulfonamides, spiramycinm clindamycin, macrolides, hydroxynaphtoquinones, folate inhibitors, immunomodulators, and other combination drugs. Geographically, the global taxoplasmosis encephalitis market can be categorized into four major regions viz. North America, Europe, Asia Pacific, and Rest of World. In the U.S., toxoplasmic encephalitis is mostly caused by reactivation of chronic infection in patients with HIV. Moreover, the incidence of this disease has a direct correlation with the presence of antibodies against T. gondii. Approximately 10% to 40% of patients with HIV in the U.S. manifest presence of antibodies against T. gondii.

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Various studies indicate that 50% of T. gondii-seropositive AIDS patients develop toxoplasmic encephalitis in a due course of time. The risk of toxoplasmosis decreases after administration of a primary prophylaxis against T. gondii and recommendation of effective therapy against the retrovirus. Prevalence of the asymptomatic infection usually increases with the age. Seroprevalence rates of this parasitic infection have been declining worldwide. However, it is observed to be high in South America, Africa, and Europe. Furthermore, in some of these places, rates may be still increasing. Some of the key players operating in the global taxoplasmosis encephalitis market include DiaSorin, Glenmark, GlaxoSmithKline, Hoffman La Roche, and Boehringer Ingelheim.

Smart Insulin Pens Market Share and Growth Factors Impact Analysis 2017 - 2025

Smart insulin pens are insulin injection delivery devices that can be connected with computers and smartphone apps. Diabetes management with conventional insulin pens is time consuming and difficult to maintain dosage data. Technological innovations and advancements have brought about major changes in the diabetes management industry in the last decade. Large technological advancements in diabetes management, particularly in connectivity of devices with mobile, smart insulin pens with timing and memory function have greatly improved the quality and efficiency of insulin pens. This connected device helps to track insulin dosage data, send dosage reminders, and manage data. These devices are either connected via standard Bluetooth technology or via USB connection. Manufacturers are focusing on introducing insulin injection pens with smart connectivity. The first generation of smart pens comprised only smart reusable insulin pens. However, several manufacturers are focusing on the development of disposable smart insulin pens.

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Prevalence of diabetes is expected to increase exponentially across the globe owing to changes in lifestyle and factors such as genetic mutations, malnutrition, and others. According to various government and private organizations operating in the diabetes industry, diabetes is considered one of the top fatal diseases. According to the American Diabetes Association, diabetes accounts for nearly 71,000 deaths in the U.S. each year. Additionally, penetration of smart insulin pens is higher among type 1 diabetes patients to manage the daily insulin requirements. Increase in incidence of T1D among kids is a major health care concern. According to the IDF, Europe had 140,000 kids (0 years to 14 years) with T1D in 2015, and 21,600 new cases are diagnosed every year. Advantages of smart insulin pens over traditional insulin pens and increase in awareness programs are the other factors likely to boost demand for smart insulin pens during the forecast period. However, the gradually increasing adoption of alternative products such as insulin pumps and insulin patches hampers the growth of the smart insulin pens market.

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The global smart insulin pens market can be segmented based on application, connectivity type, distribution channel, and region. In terms of application, the market can be categorized into type 1 diabetes management and type 2 diabetes management. Based on connectivity type, the global smart insulin pens market can be bifurcated into Bluetooth smart insulin pens and USB smart insulin pens. In terms of distribution channel, the market can be classified into hospital pharmacy, online sales, retail pharmacy, and diabetes clinics/centers.

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Geographically, the global smart insulin pens market can be segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. Europe dominated the global market due to high awareness among diabetes population and early launch of technologically advanced smart insulin pens. Developed countries such as Germany, the U.K., and France are the major markets for smart insulin pens in the region. Europe accounts for a substantially larger share of the global smart insulin pens market, followed by North America. Factors such as large number of people diagnosed with diabetes, technological advancements, extensive R&D practices, and growing awareness about the treatment and management of diabetes among type 1 patients drive the smart insulin pens market growth in North America. Increase in demand for smart insulin pens in countries such as China, India, and Japan is expected to propel the smart insulin pens market in Asia Pacific. Moreover, increased incidence of diabetes and rise in penetration of insulin pens over syringes are the other factors augmenting the market in the region. However, affordability and lack of availability of innovative smart insulin pen products restrains the smart insulin pens market in developing and underdeveloped regions such as Latin America and Middle East & Africa. Despite this, the market in these regions is expected to witness gradual growth, with contribution from developing countries such as South Africa and Brazil. Major players operating in the global smart insulin pens market include Digital Medics Pty Ltd., Emperra GmbH E-Health Technologies, Companion Medical, Inc., and Biocorp.

Friday 23 February 2018

Drug and Alcohol Rehabilitation Market : Competitive Landscape Analysis with Forecast by 2025

The process of combining medical and psychotherapeutic treatment to address the dependence on alcohol and drugs such as prescription drugs and street drugs is called rehabilitation. Addiction to alcohol and drugs is considered a chronic disease. If the addiction is untreated, it can have serious life threatening effects. Drug and alcohol addiction is treated with several steps such as detoxification, counselling, medication, and long term follow ups to avoid relapse. Withdrawal symptoms are serious such as sweat, nausea, and vomiting. Hence, addiction is considered treatable, but a complex process.

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The global drug and alcohol rehabilitation market is expected to expand at a significant growth rate during the forecast period. According to the National Institute on Alcohol Abuse and Alcoholism, 26.9% of people aged 18 and above were engaged in binge drinking in a month in 2015. Rising prevalence of alcoholism is likely to be a key factor driving the global market from 2017 to 2025. Increased usage of illegal drugs is another factor anticipated to propel the global market during the forecast period. Furthermore, rise in major depression disorders, surge in trend among youngsters toward drugs and alcohols, underage drinking, peer pressure, and self-medication are some of the factors projected to fuel the growth of the global drugs and alcohol rehabilitation market during the forecast period. Serious withdrawal symptoms of the treatment is a major factor anticipated to restrain the global market from 2017 to 2025.

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The global drugs and alcohol rehabilitation market can be segmented based on treatment, screening, end-user, and region. In terms of treatment, the global market can be segmented into counselling, medication, and behavioral treatment. The medication segment can be sub-segmented into opioid addiction, tobacco, alcohol, and others. The medication segment is expected to account for a significant share of the global market during the forecast due to increase in usage of illicit drugs, alcoholism, and self-medication. Based on screening, the global market can be divided into oral fluid drug screening, urine drug screening, breathe alcohol screening, hair analysis, and others. In terms of end-user, the global drugs and alcohol rehabilitation market can be segmented into rehabilitation centers and clinics, hospitals, and home care settings. The rehabilitation centers and clinics segment is anticipated to hold the largest share of the global market during forecast period due to factors such as increasing federal funding.

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The global drug and alcohol rehabilitation market is projected to expand at a significant growth rate across regions. Geographically, the global drug and alcohol rehabilitation market can be divided into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America dominates the global market in terms of value. Factors attributed to the growth of the market in North America are increase in patients suffering from major depression, prevalence of unhealthy lifestyle, surge in drug trafficking, and peer pressure. Europe is anticipated to account for the second largest share of the global market due to highest number of alcoholism-related disorders in the region. The market in Asia Pacific is expected to experience high growth due to increase in alcohol usage.
To maintain a significant position in the global drug and alcohol rehabilitation market, the key players are adopting strategies such as mergers and acquisitions, robust research and development, and geographical expansion. Major players operating in the global drug and rehabilitation market are Indivior, Inc., West-Ward Pharmaceuticals Corp., and Pfizer, Inc., among others.

General Surgery Devices Market : Competitive Landscape Analysis with Forecast by 2025

General surgery devices are used for a wide variety of diseases. These devices are employed for routine procedures or in complicated surgeries. Over the time, several innovative devices have been invented for serving a particular purpose with more ease while performing surgeries and for reducing discomfort after the surgery. General surgery devices are used in gastrointestinal problems, trauma and burn care, hernias, and breast cancer. These devices are employed in several sub-specialties of general surgery such as orthopedics, obstetrics, neurology, urology, cardiovascular, and gynecology. The key purpose of general surgery devices is to cut, clamp, grasp, tie, and spread anatomical parts of the human body during surgical procedures. These devices are deployed primarily in hospitals, small clinics, and health care centers.

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The increasing number of geriatric patients worldwide, awareness among patients about different surgeries and minimally invasive procedures, technological developments in surgical procedures such as robotic and power-assisted systems are factors likely to fuel the general surgery devices market in the next few years. One of the technological developments is that the market is witnessing preference to minimally invasive procedures and use of robotics and computer-assisted devices, thereby reducing time required for surgery as well as complications. This has opened new avenues for growth of the global general surgery devices market. Market players are competing with one another with new product launches, expanding geographic presence, and innovative and educational offerings. However, the market is also facing challenges such as development of other non-invasive surgery technologies and intense competition among existing manufacturers of general surgery devices. Moreover, factors such as product recalls, government regulations regarding reduction in overall health care costs, and subsequent increase in bulk purchasing through INHs (Integrated Health Networks) and GPOs (group purchasing organizations) are restraining the market.

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The general surgery market have been segmented by product, application, and geography. In terms of product, it can be segmented into disposable surgical supplies, reusable, minimally invasive surgery instruments, energy-based and power devices, adhesion prevention products, and medical robotics and computer-assisted surgery devices. Among them, the disposable surgical supplies segment leads the market, due to rising demand for disposable needles, syringes, and catheters.

Geographically, the general surgery devices market can be classified into North America (U.S. and Canada), Europe (Germany, France, the U.K., etc.), Asia Pacific (Australia, China, Japan, and India), Latin America, and Middle East & Africa. The emerging markets in Asia Pacific, Latin America, and Middle East & Africa are expected to witness robust growth during the forecast period. North America leads the global market, holding the maximum share. This can be attributed to strong policy support of governments, favorable reimbursement policies, and the increase in demand for surgeries led by lifestyle-related diseases in the region. However, in terms of growth rate, Asia Pacific is likely to surpass all other regions in the next few years, due to the increasing expenditure on health care in developing countries of the region. Some of the prominent markets in Asia Pacific are India, Japan, China, Australia, and Singapore.

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Some of the key players operating in the global market for general surgery devices are B. Braun Melsungen AG, Boston Scientific Corporation, Smith & Nephew, Covidien Plc (Medtronic), Integra LifeSciences, Conmed Corporation, 3M Healthcare, CareFusion Corporation Ethicon, Inc. (Johnson & Johnson), Integra LifeSciences, Erbe Elektromedizin GmbH, TransEnterix, Inc., and Integer Holdings Corporation.

Mammography Systems Market Scope and Opportunities Analysis 2017 – 2025

Mammography system is a special imaging medical device that helps detect breast cancer or breast-related diseases in women experiencing symptoms such as nipple discharge, skin dimpling, pain, or lump. This is done by the use of lower dose of X-rays and ionizing radiations. Even before the women experience symptoms of cancer, the mammography system is useful in detection. Mammography system shows changes in breast up to two years before a physician or a patient can feel them. A mammography system is a box with a tube to produce X-rays. According to the Breast Cancer Organization, globally, breast cancer is one of the significant health issues among women, as more than 30% (over 3.1 million women in the U.S.) were anticipated to have breast cancer among the cancer diagnosed patients in 2017. Among the women in the U.S., other than skin cancer, breast cancer is the most prevalent disease as about 85% of women diagnosed with breast cancer have no family history of the disease.

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Increased awareness about early detection of breast cancer and related disorders due to proactive initiatives by health care organizations, rise in geriatric population, increased prevalence of breast cancer, advancements in research and technological developments such as breast tomosynthesis, rise in government funding for breast cancer, and improved reimbursement insurance policies drive the global mammography systems market. However, generation of false negative or positive results and radiation exposure risks are anticipated to restrain the global mammography systems market.
The global mammography systems market can be segmented based on product type, technology, end-user, and region. In terms of product type, the market can be divided into breast tomosynthesis systems, analog mammography systems, and digital mammography systems, which can be sub-divided into digital radiography systems and computed radiography systems. The digital mammography systems segment held significant market share in 2016 owing to technological advancements. The breast tomosynthesis systems segment is anticipated to gain market share during the forecast period due to FDA approval for safe levels of radiation from mammograms, benefits such as clearer images, greater likelihood of detecting multiple breast tumors, fewer unnecessary additional tests or biopsies, greater accuracy, and early detection.

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Based on technology, the global mammography systems market can be segmented into 3-D mammography, 2-D mammography, and combined 2-D and 3-D mammography. The 3D mammography segment accounted for large market share in 2016 owing to factors such as false alarm, and the Medical Imaging Modernization Act, 2015. The combined 2-D and 3-D mammography segment is anticipated to grow in the next few years due to increasing awareness and government initiatives for breast cancer.

In terms of end-user, the global mammography systems market can be classified into ambulatory surgical centers and inpatient settings. Geographically, the global mammography systems market can be segmented into Asia Pacific, Europe, North America, Latin America, and Middle East & Africa. North America held significant market share in 2016 due to rise in population of women above 40 years, number of mammography units in diagnostic centers and hospitals, reimbursement coverage by governments, and sophisticated health care facilities. The market in Asia Pacific is anticipated to grow during the forecast period driven by high prevalence of breast cancer due to change in lifestyle of women in emerging countries such as China and India.

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The major companies in the global mammography systems market include Siemens Healthcare GmbH, FUJIFILM Corporation, General Electric Company, Koninklijke Philips N.V., Analogic Corporation, and other prominent players are Toshiba Medical Systems Corporation, Planmed Oy, Konica Minolta, Inc., Hologic, Inc., Carestream Health, Tualatin Imaging, P.C., Micrima Limited, Delphinus Medical Technologies, Inc., and Aurora Imaging Technology, Inc.

Antiseptic First Aid Liquids Market: Current Trends and Future Aspect Analysis 2017 - 2025

An antiseptic is a chemical agent that destroys or inhibits microorganisms on living tissue such as oral cavities, skin, and open wound. A few antiseptics are capable of destroying microorganisms and are termed as bactericidal (hydrogen peroxide, mercurochrome). Only a few of these are capable of preventing or inhibiting the growth of microorganisms and are termed as bacteriostatic (alcohol, phenol). Primary application areas of antibiotics include hospitals, clinics, laboratories, and households. Examples of antiseptic liquid include alcohol, phenol, quaternary ammonium compound, brilliant green, hydrogen peroxide, iodine solution, polyhexanide, and sodium bicarbonate. Hand sanitizers are liquid antiseptics widely used to keep hands clean and avoid illnesses such as flu. Using hand sanitizers before eating and before working on a patient or an open wound can significantly reduce the chances of contamination for the patient. First aid antiseptics help relieve pain and prevent infection in cases of minor cuts, scrapes, and burns. Common active ingredients in antiseptic products are benzethonium chloride, benzalkonium chloride, lidocaine hydrochloride, benzocaine, and ethyl alcohol.

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The global antiseptic first aid liquids market is growing rapidly driven by increase in number of surgeries performed for various diseases and disorders. Growth of the market in terms of revenue is attributed to outbreak of infectious diseases such as swine flu. Such incidences have increased public awareness about the potential dangers of such infections. Rise in public awareness also boosts market growth primarily in the developed countries. Furthermore, rise in the number of hospitals, health care centers, and advanced health care facilities are likely to propel the global antiseptic first aid liquids market. Also, an increase in awareness and knowledge regarding precautions to be taken to prevent from flu, bacterial and other viral infections have driven the growth of this market. However, saturated market and stringent regulations in the developed economies are likely to restrain the antiseptic first aid liquids market.

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Various chemical compounds are used as antiseptic first aid liquids. Hence, these are categorized based on chemical composition. The global antiseptics first aid liquids market can be segmented based on chemical compound and end-user. In terms of chemical compound, the market can be categorized into alcohols and aldehydes, amides and biguanides, quaternary ammonium compounds, phenol and its derivatives, iodine compounds, and others. The alcohol and aldehyde derived segment is projected to account for the largest market share, followed by the amide and biguanide segment. Examples of antiseptic first aid active ingredients are camphorated phenol, benzethonium chloride, iodine, chloroxylenol, and povidone-iodine. In terms of end-user, the market can be segmented into hospitals and household.

Geographically, the global antiseptic first aid liquids market can be segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America and Europe dominate the global market due to increased awareness among people. Asia Pacific and MEA hold the third and fourth positions in the global antiseptic first aid liquids market due to lack of awareness in some remote areas in the developing and underdeveloped nations.

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Key players in the global antiseptic first aid liquids market include Ayuroma International Pte. Limited, Schulke & Mayr UK Ltd., Pascal International, Inc., Zhermack SpA, Dynarex Corporation, Dexcel Pharma GmbH, Reckitt Benckiser, Huckert International, and Sirmaxo Chemicals Private Limited.

High Performance Liquid Chromatography Market Share and Growth Factors Impact Analysis 2017 - 2025

High performance liquid chromatography (HPLC) is one of the techniques used to separate, quantitate, and identify components in the given mixture. It is considered one of the powerful tools in analytical chemistry. HPLC is a type of column chromatography in which the solvent containing the sample mixture is passed through a column containing adsorbent material, using a pressure pump. The component in the sample reacts differently with the adsorbent material, leading to different flow rates of different components, thus separating the mixtures. This process is faster as compared to other chromatography procedures.

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The global HPLC market is expected to expand at a robust CAGR over the forecast period. Greater sensitivity and higher accuracy as compared to conventional chromatographic techniques are the significant factors likely to drive the growth of the global HPLC market over the forecast period. Higher penetration rate of HPLC, increased popularity of LC-MS (liquid chromatography- mass spectrography), surge in usage of HPLC in pharmaceuticals for quality control testing and manufacturing, faster results and separation, and technical advancement are some of the other factors propelling growth of the global market through 2025. Furthermore, growing number of pharmaceuticals in developing and developed countries is anticipated to drive the growth of the global HPLC market. However, high cost of the instrument and lack of expert analysts are factors restraining the growth of the global high performance liquid chromatography market.

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The global HPLC market can be segmented on the basis of product type, application, end users, and region. On the basis of product type, the market can be segmented into instruments, consumables, and accessories. The consumable segment is expected to register highest share during the forecast period, due to its high usage. The instrument segment can be sub segmented into pressure pumps, detectors, fraction collectors, systems and others. Based on application, the global HPLC market is divided into diagnostics, manufacturing and quality control testing, clinical research, forensics and other application. The manufacturing and quality testing segment is anticipated to register considerable market share during the forecast period due to faster results with greater accuracy and higher sensitivity. Based on end users, the global HPLC market can be divided into pharmaceutical industries, academic and research institutes, diagnostic laboratories and others. The pharmaceutical industries segment is expected to register the highest growth during the forecast period due to rise in number of industries.

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The global HPLC market is projected to expand at a significant rate across regions. Geographically, the global HPLC market is divided into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America is the dominating region in the global HPLC market in terms of value and volume. The factors attributed to the growth of the market in North America are - developed healthcare infrastructure, increase in number of industries over a period, high adoption rate of technologically advanced products, rise in healthcare expenditure, and expertise and research activities in the region. Asia Pacific is expected to witness higher growth in the global HPLC market due to factors such as newer technology, rise in disposable income, and increasing funding for research activities.

To maintain a significant position in the global HPLC market, key players are following strategies such as developing user friendly and cost effective products, mergers and acquisitions, robust research and development, geographical expansion etc. Some of the prominent players operating in the global HPLC market include GE Healthcare, WATERS, Bio-Rad Laboratories, Inc., Shimadzu Corporation, Thermo Fisher Scientific Inc, Gilson, Inc., and Higgins Analytical, Inc.

Thursday 22 February 2018

Testosterone Replacement Therapy Market is exhibiting a (-4.2)% CAGR by 2024

Some of the key players in the global testosterone replacement therapy market include names such as Allergan Plc., AbbVie Inc., Bayer AG., Eli Lilly and Company, Endo Pharmaceuticals, Kyowa Kirin International Plc., Novartis AG., Mylan N.V., and Pfizer Inc. among others. The global market for testosterone replacement therapy is a little bit consolidate with the existence of a few big established companies and the presence of some domestic vendors that are playing their trade in the global market. Companies are now focusing on product development and innovation to enhance their market presence. Recently, Pfizer’s new drug, Mylotarg, has been approved by the U.S. Food and Drug Administration, for certain patients who suffer from acute myeloid leukemia (AML). More and more companies are inclining towards getting their products sanctioned and get into the market. This will in turn, help in intensifying the competitive market landscape of the global testosterone replacement therapy market over the course of the given forecast period of 2016 to 2024. The top five companies in the global market held over 80% of the total market share in the 2015 out of which AbbVie Inc. has come up on top as the undisputed leader.

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The global market is expected to reach an overall valuation of US$1.3 bn by the end of 2024. This valuation is lower than that found in the year of 2015 of US2.0 bn. The market will show a negative CAGR of -4.2% over the course of the forecast period of 2016 to 2024.

Increasing Number of Hypogonadism Patients Drive Global Testosterone Replacement Therapy Market

Hypogonadism or more commonly known as the testosterone deficiency is a prevailing problem found in men that are aged between 40 to 79 years. Some studies also suggest that nearly 30% of the men across the globe are impacted by this testosterone deficiency problem. As the occurrence of such cases increase in number, the demand for testosterone replacement therapy is also expected soar subsequently.

Along with this major factor, another important driving factor for the growth of the global testosterone replacement therapy market is the increasing geriatric population across the world at a steady pace. This points to huge demographic target for the companies in the global testosterone replacement therapy market. It is expected that number of men reporting deficiency of testosterone will increase across the world as the number of older population will rise. In addition to these two factors, there is a growing awareness among the world population about the deficiency of testosterone and they are taking measures to tackle the problem. This will subsequently help in boosting the growth prospects of the global testosterone replacement therapy market.

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Ill Effects of Testosterone Replacement Therapy May Impede Market Growth

However, there are some problems which are projected to cause some problems in the development of the global testosterone replacement therapy market. There is a modest level of apprehension among people about the side effects caused due to the use of the testosterone replacement therapy. Risk of developing metabolic and cardiovascular diseases is also impeding the growth of the market of testosterone replacement therapy products. There are several studies and reports which have indicated the ill effects of the therapy owing to which FDA has issued ample warnings about the possible risks. This has caused a large number of patients to see the testosterone replacement therapy in a negative shade of light.

In addition to this, the global market is nearing a cliff related to the patent approval issue. It is expected that the market for testosterone will face a problem of imminent expirations of patents and may lead to impeding the growth of the market in the coming years. However, with several drivers working in favor of the therapy, the market will witness a steady growth during the given forecast period of 2016 to 2024.

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Cardiac Rehabilitation Market will rise to a valuation of US$1,622.9 mn by 2024

The global cardiac rehabilitation market largely consist of a few strong players who exert control over the entire market. This makes the vendor landscape immensely consolidated, thus, barring the entry and establishment of new players. Transparency Market Research (TMR) prognosticates that product innovations would play a major role in deciding the course of the competitive landscape. The leading market players are expected to keep introducing novel products to retain their dominance in the market. The top two market players viz. Technogym and Brunswick Corporation held more than 50% of the total market share in 2015. The other two key players, Amer Sports and Johnson health Tech Co. are also on the run for a greater market share. All the companies mentioned above collectively accounted for approximately 70% of the global market share in 2015. There are tremendous opportunities for investors because the market is buzzing with the advent of new technologies. The rivalry amongst the established players has been intensifying and the demand in the market has been rising. Owing to these factors, there are lucrative opportunities resting within the market.

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The estimations made by Transparency Market Research portray that the market stood at a value of US$1,010.93 mn in 2015 and is expected to elevate to a value of US$1,622.9 mn by the end of 2024. It is also projected that the market would grow at a sturdy CAGR of 5.40% over the period from 2016 to 2024. Based on the type of devices, the highest demand was attracted by elliptical trainer segment. The segment accounted for 27% of the total demand and this owes to the multiple uses of such devices. Geographically, North America has reigned over all other regions in terms of demand, accounting for 50% of the global demand. Asia Pacific is expected to register a CAGR of 6.80% over the period from 2016 to 2024.

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Measures to Bring Down Mortality Rates Uptick Demand

The global market is driven by the rising instance of cardiovascular diseases. The wayward lifestyles of the populace have increased the risk of diseases and have adversely affected the heart rates of individuals. In recent times, the initiatives of healthcare centers to inform people on the importance of cardiovascular health has created a sense of awakening across the world. This has proliferated the demand within the cardiac rehabilitation market. Furthermore, cardiac disorders, dysfunctions, and diseases have contributed to the high rates of mortality and morbidity. The quest of national governments to enhance the healthcare index has driven the demand for cardiac rehabilitation. The geriatric population has also been on a rise in recent times, which further escalates the demand for cardiac rehabilitation. Since the risk of cardiovascular diseases in people aged above 60 years, it is vital to have a swift mechanism of treatment for this section of the population. The concerted efforts of international bodies such as the WHO are expected to enhance the market.

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High Costs of Cardiac Rehabilitation Products Could Obstruct Market Growth

The technologies employed within the domain of cardiac rehabilitation are complex and expensive. This makes the cost of products within the market unaffordable for a large population. The restraints on the market intensify when new technologies outdo the cardiac rehabilitation products. The high capital and intensive research employed in cardiac rehabilitation products make it difficult to regulate the costs. Furthermore, the enrolments in cardiac rehabilitation programs are low which adds to the woes of the market. However, the formulation of flexible schedules for cardiac rehabilitation programs can help in overcoming this problem. 

Opioid Induced Constipation Treatment Market to Become Worth US$4.8 bn by 2023

Takeda Pharmaceuticals Company, Ltd., with its approved drug Amitiza, holds a majority share in the global opioid induced constipation treatment market. In 2014 the top three players - Takeda, Valeant Pharmaceuticals International, Ltd., and Boehringer Ingelheim – operated on a collective share of 91.8% of the global market.

This is a highly consolidated market but with a large scope for the prominent players to penetrate regions other than North America.

Transparency Market Research’s recent publication reveals the possibilities that players in the global market for opioid induced constipation treatment can take up to improve their global standing in the market. This includes reaching out to the emerging economies and gain shares from a currently untapped market.

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The global market for opioid induced constipation treatment is expected to progress at a highly positive CAGR of 31.2% within a forecast period from 2015 to 2023 with respect to revenue. By the end of 2016, this market is expected to generate US$731.2 mn, which is projected to reach US$4.81 bn by the end of 2023.

Chloride channel activators are the more popular drug class among all opioid induced constipation treatments currently available. Over time, PAMORAs are expected to overtake them owing to a large number of pipeline drugs close to approval. By the end of 2023, PAMORAs are expected to generate a revenue of US$2.41 bn.

North America to Continue Generating Leading Demand for OIC Treatments

North America is expected to continue dominating the demand for opioid induced constipation treatments till 2023, owing to a majority consumption of opioids. The American Society of Interventional Pain Physicians has stated that in 2013, the U.S. alone was responsible for nearly 80% of the global consumption of opioids. Key reasons for this high consumption include the legal acceptance of opioids for pain treatment by the U.S. FDA, and the high awareness consumption level of opioids for the long term treatment of chronic pain.

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By the end of 2023, it is predicted that North America will generate US$4.05 bn in revenue for the providers of opioid induced constipation treatments.

A secondary reason for this high volume of consumption is also related to the extremely low awareness rates of available opioid induced constipation treatments in other regions.

Multiple OIC Drug Approvals Imminent, Demand Expected to Rise Accordingly

“Most certainly the leading driver for the growth in demand of opioid induced constipation treatments is the awaited approval of several drugs that are in the pipeline. Naldemedine is one of the stronger contenders which is expected to be released before the end of 2016,” states a TMR analyst.
Furthermore, the increasing development rate of peripheral mu-opioid receptors is expected to generate a giant boost to the preference of OIC-specific treatments. PAMORAs allow for the effective treatment of OIC without interfering in the opioids action on the patient’s pain.

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Standard Laxatives Still Considered a Challenge to OIC Treatments

One of the greater restraints currently acting on the demand for opioid induced constipation treatments is the widespread consideration of standard laxatives for countering OIC. The primary reason for this is the high disparity between the pricing of standard laxatives and targeted OIC drugs.
At the same time, the relatively under-researched position of opioid induced constipation treatments needs to be worked on. Most of these drugs are showing several adverse effects, including nausea as well as increasing the risk of heart problems and strokes.

“A way out for opioid induced constipation treatments is to improve the scope of development to reduce their side effects and improve efficacy. There is currently a giant untapped market for opioid induced constipation treatments across the world, and investing more in marketing and R&D will definitely help players penetrate it,” adds the analyst.

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Key Takeaways:
  • Solid drugs are expected to generate US$4.48 bn in opioid induced constipation treatment by 2023.
  • Mu-opioid receptor antagonists expected to generate US$2.41 bn in opioid induced constipation treatment drug classes by 2023.
  • North America expected to create US$4.05 bn in opioid induced constipation treatment by 2023.

Knee Cartilage Repair Market to Become Worth US$2.7 bn by 2023

Transparency Market Research has estimated that the global knee cartilage repair market will reach the value of US$2.7 bn by the end of 2023, from its initial value of 1.6 bn in 2014. The market is expected to exhibit a growth trajectory of CAGR 5.80% during the forecast period of 2015–2023.

Geographically, North America held a dominant share in 2014, accounting for 40.7% share of the global market. This region is expected to sustain its leading position over the forecast period owing to introduction of technologically advanced products, rise in incidence of obesity, and increase in orthopedic procedures.

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Increase in Geriatric and Obese Population to Fuel Growth

The global market for knee cartilage repair is driven by changing lifestyle and increase in geriatric population around the world, along with growing trend of outdoor events and sports activities among young as well as old generation. The sedentary lifestyle and unhealthy dietary regimen followed by population in urban areas have resulted in increasing incidence of conditions such as arthritis among urban population. Furthermore, the lifestyle followed by urban population doesn't focus more on regular exercises, which makes bones and joints more vulnerable towards injuries. Obese and the elderly populations are highly disposed to degenerative diseases such as rheumatoid arthritis, osteoarthritis, and other strain injuries. The other key factors driving the growth of the market for knee cartilage repair are increase in number of falls leading to severe knee damage and deformities, industrial accidents, and road accidents.

Knee cartilage repair is advantageous for conditions such as slow-healing wounds, delayed unions, and mal-unions. Innovation are being carried out in the development of knee cartilage repair equipment and products, which is further expected to help the market expand.

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Side Effects Due to Off-Label Practice act as Restraining Factor

Lack or poor reimbursement in developing nations encouraging innovative technologies is limiting this market to grow at its full potential. Furthermore, due to negative media information pertaining slow tissue recovery and side effects due to off-label practice of particular equipment are acting as restraining factors for this market. However, growth in arthroscopic chondroplasty segment is expected to sustain the overall market for knee cartilage repair over the forecast period. This is a procedure in which the injured tissues are removed, which helps new and strong cartilage to grow. Arthroscopic chondroplasty is used prominently for meniscal tears, and rise in number of meniscal tears is expected to expand the market for arthroscopic chondroplasty. Furthermore, increasing prevalence of obesity and diabetes are most likely to fuel the market growth. Diabetes results in loss of cartilage, making patients more prone to bones and joints injuries. Latin America and MEA region are highly subjected to increasing obese population, fueling the demand for advanced cartilage repair products helping the overall market to grow.

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The global knee cartilage repair market is highly consolidated as the top five players operating in this market accounted for 74.7% of the overall market in 2014. These players are DePuy Synthes, Smith & Nephew plc, Zimmer Biomet Holdings Inc., B. Braun Melsungen AG, and Stryker Corporation. Transparency Market Research (TMR) has revealed that these companies have established firm roots in the market and are focusing on product innovation and engaging in strategic mergers and acquisitions to remain at fore. 

Parenteral Nutrition Market to Become Worth US$6.9 bn by 2023

Braun Melsungen AG, Fresenius SE & Co. KGaA, and Baxter International, Inc., who collectively held 71% of the global parenteral nutrition market, are focusing on improving their line of products, reports Transparency Market Research. The trend of winning approvals for their new formulations from concerned authorities is also helping them gain a significant footprint in the market, observes TMR.

Strategic joint ventures are also being considered by companies to expand their businesses and enhance their product portfolio in the near future. “Plans to expand manufacturing facilities are also underway. This move will help companies ensure utmost safety, unquestionable quality, and remarkable efficiency of the product,” asserts the head analyst of this report.

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Parenteral Nutrition Becomes Critical to Saving Lives - A Key Growth Enabler

The focal point of parenteral nutrition is to provide chronically ill patients adequate nutritional support. The high incidence of chronic conditions such as cancer, gastro-intestinal disorders, ischemic bowel disease, diabetic complications, and Crohn’s disease amongst others is propelling the demand for parenteral nutrition. As this form of oral nutritional supplement becomes the only way of treating the immobilized patient, the demand for these nutrients is witnessing a phenomenal rise.
According to the World Health Organization about 11% of the global burden of disease is due to malnutrition and is considered to be a huge risk to human life. As this number will increase in the coming years citing issues of political unrest, food security, and changing environmental conditions, the demand for parenteral nutrition will remain persistent.

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Side Effects of Parenteral Nutrition Hamper Market Growth

The global parenteral nutrition market faces the huge risk of health complications due to poor monitoring. The American Society for Nutrition also stated that prolonged usage of parenteral nutrition therapy can lead to metabolic complications and liver diseases. Furthermore, shortness of breath, allergic reactions, muscle pain, and unexplained weight gain are also hampering the growth of this market.

However, a large patient pool in emerging economies of China, Brazil, India, and Brazil offer a tremendous scope for growth to the parenteral nutrition market. Furthermore increasing investment by leading players in the developing regions of Asia Pacific and Latin America to increase production of parenteral nutrition is also expected to create large opportunities to register a high growth.

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Large Patient Pool in Asia Pacific Makes it Leading Segment

The research suggests that the opportunity of the global parenteral nutrition market will be worth US$6,874.1 mn by the end of 2023 from US$4,097.4 mn in 2014. The market is expected to expand at a steady CAGR of 5.7% from 2015 and 2023. On the other hand, Asia Pacific will the key geographical segment as it will expand at a CAGR of 7.3% in the forecast period due to growing cases of chronic diseases such as cancer and AIDS. The parenteral lipid emulsion nutrient segment will grow at the highest CAGR of 6.2% during the same forecast period, leading the overall nutrient segment.

Key Takeaways:
  • High prevalence of chronic diseases and related malnutrition speeds up consumption of parenteral nutrition in healthcare facilities.
  • Seeking approvals for new formulations becomes an important strategy for companies to gain market presence.
  • Large patient pool and high incidence of cancer and AIDS makes Asia Pacific an attractive market.
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EME Blood Gas and Electrolyte Analyzers Market to Become Worth US$170.5 mn by 2024

The Europe and Middle East (EME) blood gas and electrolyte analyzers market features a highly consolidated competitive landscape, wherein the top three vendors: Radiometer, Siemens Healthcare, and Instrumentation Laboratories, held more than 65% of the market in 2015, observes Transparency Market Research (TMR) in a recent report. The market has seen a remarkable shift in consumer preference from traditional table-top devices to handheld portable ones in the past few years.
This factor is expected to direct the focus of key manufacturers and a vast share of their research and development funds and activities to the latter in the near future. “However, the choice of blood gas and electrolyte analyzing devices is largely governed by the suitability of a particular type for the concerned healthcare facility. Thus, although portable point-of-care devices will conquer majority of the market of traditional devices, they will not be able to completely replace them, especially when it comes to applications requiring high volume measurements with a high rate of accuracy.” points a TMR analyst.

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Combination Devices Segment to Lead to Most Promising Returns

It is estimated that the EME blood gas and electrolyte analyzers market will expand at a CAGR of 4.7% in terms of revenue from 2016 to 2024. At this pace, the market, which held an opportunity of US$114.4 mn in 2015, is expected to rise to US$170.5 mn by 2024. Of the key product varieties of blood gas and electrolyte analyzers in the EME market, the segment of combination analyzers is expected to be the most promising segment, expanding at a 6.1% CAGR from 2016 to 2024. In terms of overall market valuation, the segment of blood gas analyzers dominates, holding over a 50% of the market in 2015. Geographically, the market in the EU5 region holds the dominant position, accounting for a massive 74% of the overall market in 2015.

Rising Patient Burden in Healthcare Facilities Set to Bolster Adoption Rate of Advanced Analyzers

Increase in geriatric population and the rising incidences of a number of chronic diseases affecting this demographics in Europe and Middle East has led to rise in the number of patients receiving critical care in intensive care units, emergency departments, and operation rooms. This shift in patient demographics is translating into increased market opportunities for the field of blood gas and electrolyte testing. The vast rise in the number of diagnostic hospitals and centers in the region is helping unburden the rising number if patients receiving critical care. Moreover, the market is also vastly driven by technological enrichments and innovations in blood gas and electrolyte analysis devices.

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In the past few years, vast funds have also been directed towards the development of fast and reliable solutions that offer improved diagnosis for patients and clinicians in the least possible timeframe. The success of these efforts can be assessed from the fact that the market has devices capable of testing blood gas in less than a minute, with also a significant reduction in the amount of blood sample needed for test. The rising demand for such portable and fast blood gas analyzers is expected to have a significant impact on the market’s overall development in the next few years.

Dearth of Trained Resources to Hamper Adoption of Blood Gas and Electrolyte Analyzers across EME

Despite having mostly positive growth prospects, the EME blood gas and electrolyte analyzers market is expected to be restrained to a certain extent owing to the death of trained personnel in remote areas. The complex functioning and the need for understanding of data for these analyzers remains a challenge that limits the adoption of a variety of blood gas and electrolyte analyzers in home care locations. Other factors such as the recent economic crises in Europe, which had negative impact on the invitro diagnostics (IVD) industry and cost containment measures by health care facilities are also expected to hamper the growth of the blood gas and electrolyte analyzers.

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