Prepacked Chromatography Columns Market is expected to reach US$3.3 b by the end of 2024

The opportunity in the global prepacked chromatography columns market is anticipated to rise US$1.6 bn in 2015 to be worth US$3.3 bn by 2024. If these values hold true, the market is estimated to register a CAGR of 8.4% during the forecast period.
Growing Usage of Prepacked Chromatography Columns in Sample Preparation
Based on product type, the prepacked chromatography columns market is led by the >1L segment, which accounted for a share of just short of 50% in 2015. This segment is also anticipated to expand at a pace greater than the other segments, reporting a CAGR of 8.7% from 2016 to 2024. By technique, hydrophobic stationary phase chromatography held a major share in the prepacked chromatography columns market, with multimodal chromatography expanding at the fastest pace.

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On the basis of application, the sample preparation segment accounted for the leading share in the market while protein purification is forecast to report a high growth rate. Based on end use, the prepacked chromatography columns market was dominated by pharmaceutical biotechnology, and analytical laboratories are anticipated to emerge as the most lucrative end-use segment.
Geographically, North America accounted for a major share of 33.9% in the global prepacked chromatography columns market in 2015. Retaining its lead throughout the forecast period, the demand for chromatographic techniques is anticipated to rise in the region. On the other hand, Asia Pacific is poised to grow at an impressive 10.2% CAGR from 2016 to 2024.
Wide Range of Application of Prepacked Chromatography Columns a Major Growth Driver
“Prepacked chromatography columns are well suited for various industries for the separation as well as detection of organic molecules and components,” the lead analyst notes. As a result, these columns play a significant role in the production of biopharmaceutical products. Prepacked chromatography columns are also used in industries such as biotechnology, food and beverages, agriculture, chemicals, research, and forensics. This wide range of application is a key factor boosting the global market.

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“The number of monoclonal antibodies used in clinical trials and those approved for various therapeutic applications has significantly increased in recent years,” the TMR analyst states. This growing need for therapeutic monoclonal antibodies has also supported the prepacked chromatography columns market.
In contrast, the economic slowdown in several countries over the past decade has had a considerable impact on government budgets and funding when it comes to research within the healthcare sector. This has adversely impacted the global market for prepacked chromatography columns market. Moreover, the high prices of columns and limitations resulting from clogging and fouling act as deterrents to the market.
The global market for prepacked chromatography columns market is immensely consolidated, with the top two players accounting for a 78% share in the market in 2015. Of these, GE Healthcare has been the clear leader, dominating over more than half the prepacked chromatography market that year. Repligen, on the other hand, has been gaining momentum over the years, giving its competitor a run for its money by focusing mainly on single-use or disposable manufacturing facilities.

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Transparency Market Research has found that some of the smaller players have been emphasizing on strategies such as competitive pricing, offering customized products, engaging in symbiotic alliances, and expanding their product portfolio to gain a share in the global prepacked chromatography columns market. For instance, in May 2016, Agilent Technologies launched the Agilent 1260 Infinity II liquid chromatography system so as to reduce its operational costs, improve overall usability, and strengthen its position in the global market.

Intravenous Immunoglobulin Market to Reach an Opportunity of US$14.92 bn by the End of 2024

The global intravenous immunoglobulin (IVIG) market is largely consolidated, with top four players: Grifols S.A., CSL Behring LLC, Baxalta Incorporated, and Octapharma AG, accounting for over 70% of the overall market in 2015. Grifols S.A. accounted for the dominant share of 23.0%, chiefly on account of the company’s strong geographic penetration.
Oligopoly in the market has led to intense competition among top players and has compelled companies to take course of strategic mergers and acquisitions and geographic expansions. Point in case is the CSL Behring LLC’s geographic expansion by opening operations in Russia in December 2015. The company stated that the expansion was driven by large unmet need of quality biotherapeutics and blood plasma products in the country.

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Transparency Market Research estimates that the global intravenous immunoglobulin (IVIG) market, which was valued at US$7.23 bn in 2015, is projected to expand at a CAGR of 8.5% from 2016 to 2024 and reach US$14.92 bn in 2024. In terms of end users, the hospitals segment is presently leading, accounting for a more than 62% of the overall market in 2015. The segment is, however, expected to lose prominence to the home care segment and reflect a loss in its overall share by 2024. In terms of geography, North America, which presently accounts for over 45% of the global market, is expected to retain dominance by 2024 as well.

Rising Prevalence of Neurological Diseases to Boost Global Demand for IVIG Products
The rapidly rising prevalence of a variety of hematological and neurological disorders such as alloimmune thrombocytopenia, idiopathic thrombocytopenic purpura (ITP), and myasthenia gravis is the chief factor driving the intravenous immunoglobulin (IVIG) market. For instance, the occurrence of myasthenia gravis in the U.S. has been assessed at 14 to 20 cases out of 100,000 people, which comes to around 36,000 to 60,000 cases in the country. This neuromuscular transmission has a high probability of remaining undiagnosed and thus the prevalence of this disease is actually much higher. Over 40% of the world’s IVIG products are used to treat neurological diseases, thus the rising prevalence of neurological disorders is a highly significant factor of growth for the global IVIG market.
Moreover, the mounting global population of geriatrics, which is more vulnerable to diseases due to poor immunity, is also a key factor driving the IVIG market. According to the WHO, the global geriatric population is expected to increase from 524 mn in 2010 to 1.5 bn by 2050. This is anticipated to drive the increased demand for better immunological treatments, which in turn would provide opportunities for companies operating in the global intravenous immunoglobulin market. The steady rise in the use of intravenous immunoglobulin for the treatment of off-label indications a significant rise in the blood plasma yield across the globe are also likely to drive the intravenous immunoglobulin (IVIG) products market.

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High Cost of Treatment and Potential Side Effects to Hamper Market Growth
One of the key challenges that could hamper the overall development of the global IVIG market is the comparatively much higher cost of plasma collection and manufacturing processes as compared to conventional pharmaceutical manufacturing and processing products. Moreover, immunoglobulin products being derivatives of blood, they require highly sophisticated methods and equipment for collection, purification, and storage. This scenario adds to the overall cost and complexity of IVIG products and therapies.
Intravenous immunoglobulin (IVIG) preparations also have several related side effects, which could lead to serious health problems in some patients. Owing to this, patients are sometimes discouraged from continuing IVIG therapies. Side effects associated with the use of IVIG also sometimes encourage clinicians to opt for alternate therapies. This factor is likely to restrain the overall development of the intravenous immunoglobulin (IVIG) market in the next few years.

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This review of the market is based on a recent market research report published by Transparency Market Research, titled “Intravenous Immunoglobulin (IVIG) Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024.”

Radiopharmaceutical Market is estimated to reach US$7.4 bn by 2024

The global radiopharmaceutical market was valued at US$4.7 bn in 2015 and is estimated to reach US$7.4 bn by 2024, expanding at a CAGR of 5.3% from 2016 to 2024.
Nuclear Reactors Emerge as Key Source of Radiopharmaceuticals
By radioisotope, technetium-99 held the major share in the global radiopharmaceuticals market, accounting for 50.3% in 2016. The 18F segment, on the other hand, is projected to expand at a 5.5% CAGR from 2016 to 2024, higher than any other radioisotope.

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Based on source, nuclear reactors lead the overall market in terms of revenue and the segment is also poised to eaxhibit a strong growth rate through 2024. Accounting for the dominant share in the radiopharmaceuticals market by end use, hospitals are likely to contribute significantly toward the growth of this market in the coming years. The others segment, which covers laboratories and universities, is anticipated to expand at the fastest pace despite being restricted to only the MEA and Asia Pacific regions.
Based on application, oncology took the lead owing to the growing use of various radioisotopes in the treatment of different cancers. On the basis of geography, North America is the clear leader and is slated to achieve a 60.3% share in the global radiopharmaceuticals market by 2024. Asia Pacific, on the other hand, will register a 6.3% CAGR from 2016 to 2024, emerging as the fastest expanding regional market in terms of revenue.

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Rising Incidence of Chronic Diseases Propelling Demand for Radiopharmaceuticals
The growing incidence of cancer and cardiovascular diseases – brought on by the rise in aging population, unhealthy food habits, prevalence of obesity – is one of the primary factors driving the radiopharmaceuticals market.
“The rising incidence of chronic diseases translates into the demand for diagnostic tests such as SPECT and PET, two of the latest systems used for the treatment of various cardiovascular and neurological diseases as well as cancer,” the TMR analyst states. According to the American Nuclear Society, 90% of the radioisotopes produced is used in gamma cameras or PET scan nuclear diagnostics. The remaining 10% is used in radioactive therapeutics drugs. This growing demand for diagnostic tests has a positive impact on the demand for radioisotopes and radiopharmaceuticals.
In addition to this, the rapid advancement in radiotracers and surging awareness regarding the effectiveness of radiopharmaceuticals will support the growth of the global market. On the other hand, stringent regulatory guidelines, a shortage in the supply of radioisotopes, and a shorter half-life of radiopharmaceuticals acts as impediments for the market.

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The radiopharmaceutical market is highly consolidated, wherein the top two players – Siemens Healthineers and GE Healthcare – jointly accounted for over 70% of the global market in 2015. Transparency Market Research has observed that the degree of competition is rather high in the market owing to the presence of key players with the availability of advanced technologies and potential productive sources and a high product manufacturing capacity.
“Acquisitions play an important role among established organizations because they support sales, product development, and new methods of production,” the author of the report finds. An excellent example would be AAA. The company acquired GE Healthcare S.r.L’s FDG-PET business as well as the 100% shares of Imaging Equipment Ltd. (IEL) in 2014. These moves have enabled the company in strengthening its presence across Italy, the U.K., and Ireland.

Latex Medical Disposables Market is Expanding at a CAGR of 4.9% by 2024

The latex medical disposables market is largely fragmented, with the top five companies accounting for just over 60.0% in 2015. Transparency Market Research has found that these companies, namely Top Glove Corporation, Ansell, Hartalega Holdings Bhd, C.R. Bard, and B. Braun Melsungen, have been capturing market share through technological advancements and offering a wide product range. Investing in R&D activities has also proven to be beneficial for companies competing in this market.
“While dominant players are competing by launching innovative products, regional vendors are striving to gain market share from existing players,” the lead analyst states. Companies are also offering price discounts on bulk purchases, further boosting their position in the latex medical disposables market. Although the threat of new entrants is moderate, the threat of substitutes is considerably high.

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The opportunity in the global latex medical disposables market is expected to be worth US$6.4 bn by 2024, rising from US$4.1 bn in 2015 at a modest CAGR of 4.9% therein.
Latex Gloves Most Significant Contributor in terms of Revenue
Latex gloves has been the major product segment of the latex medical disposables market, accounting for 60.4% in terms of revenue in 2015. The latex foley catheters segment is projected to expand at a CAGR of 5.1% from 2016 to 2024, emerging as the most lucrative segment thus far. By end use, the hospitals segment is expected to account for the dominant share by 2024, followed by diagnostic centers. Hospitals are also anticipated to exhibit a high CAGR throughout the forecast period.
The global latex medical disposables market is well developed in regions such as North America and Europe. However, regions such as Latin America and Asia Pacific exhibit immense potential for high growth. North America leads the global latex medical disposables market, with 33.0% share in 2016. The Asia Pacific market, on the other hand, is projected to expand at the fastest CAGR of 5.8% during the forecast period.

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Technological Advancements and Launch of Novel Products Driving Market
“Players within the latex medical disposables market have been investing in the launch of novel technologies and products that are aimed at reducing risks and infections and offering a host of benefits to the patients,” the author of the report finds.
For instance, the BARDEX I.C. infection control latex Foley catheter is clinically proven to minimize the risk of catheter-associated urinary tract infections. The catheter’s technologically-advanced formulation dramatically lessens bacterial adherence and reduces the formation of biofilm. Similarly, Medline Industries, Inc.’s three-way Foley catheter offers continuous irrigation capabilities for use after urological surgeries. The growth of the latex medical disposables market rides on such developments.

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Latex Allergies Restricting Uptake
Latex allergy is one of the most prominent challenges faced by the global latex disposables market. As a result, many healthcare providers are opting for non-latex products, thereby inhibiting the growth of the market. Leading medical technology company Becton, Dickinson and Company has found that as many as 17 million people in the U.S. are allergic to latex.
Competition is rather high in the medical disposables market, which often leads to diminishing prices of these products, including latex disposables. Shrinking or slowly increasing revenues are expected to hamper the growth of the global latex medical disposables market.

Separation Systems for Commercial Biotechnology Market to Reach an Opportunity of US$ 19,227.8 Mn by the End of 2023

The leading players, including Danaher Corporation, Thermo Fischer Scientific Inc., and Waters Corporation are putting in constant efforts to enhance their product portfolio in order to stay ahead in the global separation systems for commercial biotechnology market. These players are primarily capitalizing on prominent product segments such as liquid chromatography and flow cytometry to improve their visibility in the market, finds Transparency Market Research in a new study. The presence of a large number of players in the market is resulting in price wars.
High Government Funding in Biotechnology Sector Fuels Growth of North America
On the basis of end user, the life sciences research and diagnostics segment will continue to remain at the forefront of the market until 2023. The growing research in the field of genomics and proteomics is boosting the demand for MACs and FACs and microarray instruments in life sciences research and diagnostics sector. Owing to this factor, the segment is poised to expand at a CAGR of 7.6% during the review period.

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Geographically, North America will continue to be the leading revenue contributor until 2023, accounting for 40.7% of the overall market. The domicile of a large number of key players provides a competitive edge to the region. Moreover, high government funding for research activities in the field of biotechnology is triggering the adoption of separating systems. Asia Pacific is estimated to post a CAGR higher than any other region during the same period, due to the increasing government support and growing investments by global participants.
Continuous Innovations in Various Separation Systems Impact Market Growth Positively
Technological advancements in various types of separation systems are providing a significant boost to the global market for separation systems for commercial biotechnology. Techniques such as liquid chromatography, flow cytometry, and microarray are gaining popularity with continuous innovations in them. “These technological innovations support quick and effective separation of molecules, thereby driving their adoption,” says a TMR analyst.

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In addition, advancements in commercial biotechnology are stirring up the demand for automated separation systems. This is encouraging greater investments in research and development activities in separation systems, thereby escalating the growth of the market. Another factor that is augmenting the market is the increasing number of conferences worldwide by various private and government organizations, as these conferences help in stimulating awareness among end users regarding new separation systems.
High Cost of Chromatography Systems Hinders Market Growth
The high cost of chromatography systems and technologies is resulting in a shift in preference towards alternatives such as microextraction and electrophoresis-based techniques. Additionally, the designing and incorporation of automated features in the systems are capital-intensive, which increases the price of the whole separation systems. Thus, the high cost of these systems is hampering the growth of the global separation systems for commercial biotechnology market.

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Moreover, magnetic activated cell sorting (MACS), a technology which is considered as gold standards for cell separation, is invented and patented by Miltenyi Biotec GmbH. This is restricting the entry of new players, which in turn is acting as an impediment to the growth of the global separation systems market. However, the improving healthcare infrastructure and rising disposable income of the people in emerging economies are opening new avenues for market players.
The above data has been derived from a report by TMR, titled “Separation Systems for Commercial Biotechnology Market (Product - Liquid chromatography, membrane filters, electrophoresis instruments, flow cytometer instruments, centrifugation systems, DNA microarray instruments, protein microarray instruments, MACS & FACS systems, and biochips and lab-on-a-chip; End User - Life Sciences Research and Diagnostics, Pharmaceuticals, Food & Cosmetics, Energy, and Agriculture) - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015-2023.”

Geriatric Medicines Market to Reach an Opportunity of US$ 948 bn by the End of 2023

A recent market report by Transparency Market Research has pegged the global geriatric medicine market to reach US$948 bn by 2023. According to the report the market was valued at US$504.7 bn in 2014. The report is titled “Geriatric Medicines Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2015 - 2023,” and it projects the market to expand at a CAGR of 7.3% between 2015 and 2023.
Geriatric medicines are concerned with administering specialist medical care for elderly people. These medicines mainly deal with the diagnosis, treatment, remedial, prevention, and social aspects relating to illnesses of older people, mainly patients who are 65 years or older. The rising incidence of diseases such as cancer, neurological disorders, cardiovascular disorders, and rheumatoid arthritis has been the prime driver of the global geriatric medicine market. The market is also gaining impetus from the increasing use of multiple medicines that may cause adverse side effects.

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The global geriatric medicine market has been exhibiting growth at an impressive rate. Apart from the increasing geriatric population, rising prevalence of chronic ailments, and the increasing investments in the national healthcare systems, particularly in developing nations, will boost the global geriatric medicines market. Despite witnessing positive growth worldwide, the lack of hospitals and specialized care centers is likely to hamper the market’s growth to an extent.
The report compiles exhaustive information relating to the factors influencing the market’s trajectory. For the purpose of the study, the market has been classified based on various parameters. By therapeutic category, the report has segmented the global geriatric medicines market into antihypertensive, antidiabetic, statins, proton pump inhibitor, antipsychotic, anticoagulant, and others. Of these, the analgesic segment held the largest share in the market in 2014. The segment is also projected to continue dominating the market through the forecast period.
As per the findings covered in the report, approximately 60% to 70% of people aged 65 years or above complain of some form of persistent pain or other. The most common pain complaints among older people include musculoskeletal pain, osteoarthritic pain, chronic joint pain, and peripheral pain. The demand from the analgesic segment is therefore spurred due to the increasing incidence of such chronic pains, coupled with favorable government initiatives promoting effective healthcare.

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In terms of conditions, the global geriatric medicines market has been segmented into arthritis, cardiovascular disorders, neurological ailments, respiratory disorders, osteoporosis, and others. Of these, the cardiovascular segment accounted for the largest share in the market in 2014. The report presents insights into various factors fuelling demand from the aforementioned segments.
Regionally, the report has classified the global geriatric medicines market into North America, Asia Pacific, Latin America, Europe, and the Middle East and Africa. Among these regions, North America accounted for the dominant share of 39% in the market in 2014, trailed by Europe. However, Asia Pacific, during the forecast period, is expected to exhibit the fastest CAGR. The rising prevalence of chronic ailments and increasing geriatric population in the region, coupled with increasing expenditure on healthcare infrastructure in most developing nations will aid the expansion of the geriatric medicines market in Asia Pacific.

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To present an in-depth study on the vendor landscape, the report also profiles companies such as Bristol-Myers Squibb Company, AstraZeneca plc, Abbott Laboratories, Inc., Bristol-Myers Squibb Company, GlaxoSmithKline plc, Eli Lilly and Company, Merck & Company Inc., Pfizer, Inc., Novartis AG, and others.

Ultrasound Devices Market is expected to rise US$ 11.0 Bn by 2023

According to a TMR analyst, “The global market for ultrasound devices is expected to witness a CAGR of 5.8% between 2015 and 2023. Rising from a valuation of US$6.7 bn in 2014, the market will most likely touch US$11 bn by the end of 2023.”

Doppler Technology to be Prospect of Ultrasound Devices
The high rate of mechanical headways happening presently are relied upon to cut the street for the eventual fate of ultrasound gadgets. One of the prime product advancements is the Doppler ultrasound gadget, and it is relied upon to pick up client support and market income share at a fast rate sooner rather than later. Doppler ultrasound gadgets are to a great degree profitable for imaging of blood stream and blood maladies. The symptomatic sharpness that Doppler ultrasound gadgets can add enables medicinal staff to rapidly focus on the issue and give successful treatment. Cutting edge concepts such as pocket ultrasound devices and Doppler ultrasound devices are anticipated to pave a successful path for sales in the near future.

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Region-wise, in 2014, the leading share of 33.8% in terms of revenue was accounted by Europe. It was closely trailed by Asia Pacific. However, the market is expected to witness a paradigm shift with Asia Pacific taking over the market giant Europe and replacing it to be the leading region in the global ultrasound devices market by the end of 2023. This sudden growth of the market in Asia Pacific can be attributed to the high amount of investments being made from China along with supportive healthcare reforms, thus increasing the adoption of ultrasound devices in the region.
Growing Patent Count to Accelerate Sales of Ultrasound Devices

"Most therapeutic administrative and counseling bodies, including the WHO, concur that the quantity of patients experiencing cardiovascular ailments is developing at an alarmingly high rate," expresses a TMR expert. "The WHO clarifies that the quantity of heart patients is relied upon to cross 23 mn by 2030. This is all that anyone could need to demonstrate that human services associations around the globe are in grave requirement for cutting edge ultrasound gadgets."

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Comparative conditions can be found on account of tuberculosis, as the WHO expressed that the rising populace thickness is making it less demanding for the illness to spread and contaminate more individuals. TB is another sickness that can be successfully determined to have ultrasound gadgets, additionally boosting its request. However, the market might face little hindrances owing to the difficulty associated with the operation of these devices. Thus, to make these devices handy and light weight, researchers are focusing on making them technologically advanced enough to suit everyone’s purpose.

The global ultrasound devices market is highly consolidated with few key players leading the market, states Transparency Market Research (TMR) in a research report. Koninklijke Philips N.V., Fujifilm Holdings, and GE Healthcare were the leading companies operating in the market in 2014. In the exact same year, they collectively held a share of 67.1% in terms of revenue. This proves the level of consolidation in the market is extremely high. The vast majority of the major worldwide and provincial players figure out how to secure strong ground in this market through long haul deals contracts with clients. New contestants to the ultrasound gadgets situation won't just need to go up against the mammoth piece of the overall industry held by these best players, additionally need to oversee stores amid the costly starting period of establishment and acquisition.

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Nonalcoholic Steatohepatitis Therapeutics Market to Reach an Opportunity of US$ 20.27 bn by the End of 2025

The global nonalcoholic steatohepatitis therapeutics market is dominated by companies such as Intercept Pharmaceuticals Inc., GENFIT SA, Galmed Pharmaceuticals Ltd., Zydus Cadila, AstraZeneca plc., Gilead Sciences, Inc., and Immuron Ltd. Key companies are focusing on the introduction of new drugs and therapeutics to treat nonalcoholic steatohepatitis (NASH). As per the Natural Medical Journal, the occurrence of nonalcoholic fatty liver diseases is expected to increase in the U.S., which is likely to propel the global market in the years to come. This is anticipated to benefit the global nonalcoholic steatohepatitis therapeutics market in many ways. Transparency Market Research (TMR), in its new report, states that key companies are targeting to enhance the healthcare infrastructure and invest more on research and development activities to discover a new drug to treat nonalcoholic fatty liver diseases.

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“The prevalence of NASH in people with severe obesity is expected to be the highest,” states a TMR analyst. The global nonalcoholic steatohepatitis therapeutics market is expected to reach US$20.27 bn by 2025. Based on drug type, the global nonalcoholic steatohepatitis therapeutics market is expected to be led by elafibranor segment. The elafibranor segment is predicted to reach US$10,121.94 mn by 2025. The many benefits of elafibranor to treat NASH have made this drug type popular than others. Key companies are taking efforts to invest more into research and development activities to enhance this drug class, which is expected to propel this segment. This pipeline drug type is expected to have better prospects in the future as there are not many treatments available to treat NASH, says a TMR analysts. The rising occurrence of NASH is expected to benefit this drug type in the near future.
Key companies operating in the global nonalcoholic steatohepatitis therapeutics market are likely to increase their research and development activities to introduce new technologies to manufacture new drugs to treat NASH. The introduction of new innovative effective, and safe drugs is expected to propel the global nonalcoholic steatohepatitis therapeutics market. Manufacturers are focusing on changing government rules and drug approval procedures before introducing new drugs in the global market. Stringent government rules are expected to restrict the introduction of new drugs, which is a key challenge for the manufacturers.

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Rising obesity to strengthen global market

Nonalcoholic steatohepatitis commonly affects people with diabetes or obese people. The rising number of people with diabetes is expected to drive the demand for NASH therapeutics. The increasing pool of obese people is another factor expected to contribute towards the growth of the global nonalcoholic steatohepatitis therapeutics market. The developments in the healthcare infrastructure and therapeutic strategies are predicted to benefit the global nonalcoholic steatohepatitis therapeutics market.
Weak pipeline continues to hamper global market
A weak product pipeline is expected to hamper the growth of the global nonalcoholic steatohepatitis therapeutics market. There are not many therapies and drugs to treat NASH, which is a challenge for the leading players operating in this global market.

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Developing nations to offer new opportunities
Key companies are likely to target the developing nations to capture a significant share of the untapped market. Many emerging nations are offering growth opportunities to the leading manufacturers of nonalcoholic steatohepatitis therapeutics. The entry of new companies is also predicted to benefit the global market for nonalcoholic steatohepatitis therapeutics. However, with the entry of new companies, the global market is expected to be highly competitive in nature.
This information is based on the findings of a report published by Transparency Market Research titled “Nonalcoholic Steatohepatitis Therapeutics Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015-2025.”
The nonalcoholic steatohepatitis therapeutics market is segmented as follows:
Global Nonalcoholic Steatohepatitis (NASH) Therapeutics Market, By Drug Type

• Overview
• Potential Drug Candidates in Phase III
• Obeticholic Acid (OCA)
• Aramchol (arachidyl amido cholanoic acid)
• Saroglitazar
• Elafibranor

Cone Beam Computed Tomography Market to Reach an Opportunity of US$960.8 mn by the End of 2023

According to the research report published by Transparency Market Research (TMR), the opportunity in the global CBCT market was worth US$407.5 mn in 2014. However, analysts predict that the valuation of this market will be worth US$960.8 mn by 2023 as it expands at a steady CAGR of 10.0% between 2015 and 2023.

Rising Pool of Geriatrics to Determine Market Growth
Statistics published by the United Nations Population Division in 2013 suggested that the aging population is anticipated to reach 2 billion by the end of 2050 from 841 million in 2013. This whopping rise is likely to be the basic premise ushering in a new wave of growth for the CBCT technologies across the globe. The dental complications of the aged people are going to increase the demand for sophisticated imaging techniques in dentistry, thereby propelling the revenues earned by these technologies in the coming few years. This growth will also be complemented by factors such as the need for effectiveness in medical interventions and result-oriented research and development activities.

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Heavy Excise Duties Hamper Market
The tough excise duty imposed on the sale of medical devices across the U.S. is an unfair constraint for the CBCT market. The high cost of utilizing this technology is also holding back several institutes and healthcare centers to use CBCT technologies. TMR analyst says, “The adamancy to stick with conventional methods instead of adopting new-age technologies is also hampering the growth of the CBCT technologies across the world.”

Developing Nations Open Up Growth Options
Analysts predict that strengthening economies of Mexico, Brazil, China, and India will offer a score of opportunities to the overall CBCT market to grow in the near future. Furthermore, the increasing healthcare expenditure of these countries is also going to play a major role in the surge of this market. The improving disposable incomes of Asia Pacific are also going to contribute generously to the CBCT market in the coming years.

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The report published by Transparency Market Research states that the opportunity in the global CBCT market will be worth US$ 960.8 mn by the end of 2023. As of 2014, the market was valued at US$407.5 mn. However, the market will expand at a CAGR of 10.0% between 2015 and 2023. The report also suggests that oral surgery will be fastest-growing application segment promoting the use of CBCT technology. As of 2015, this application segment held a share of 26.4% in the overall market. Regionally, North America held a share of 41.4% in the total of CBCT market in 2015. The soaring demand for dental procedures is expected to keep this region as the leading geographical segment in the coming years.

The trend in the global cone beam computed tomography (CBCT) indicates that players must invest in developing countries to cater to consumers’ unmet medical demands and attain bigger revenue shares, says Transparency Market Research in a new report. Danaher, Planmeca, and Sirona jointly held a massive share of 70% in the global market in 2015.

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Analysts have identified Asia Pacific as the most promising region for growth in the coming few years. Furthermore, leading players are also focusing on strategic mergers and acquisitions to expand their product portfolio and their access to the customers.

Crohn's Disease Market foreseen to grow exponentially over 2017 - 2025

Global Crohn Disease Market: Snapshot
Crohn's disease, a chronic inflammatory bowel disease affecting the gastrointestinal tract, is mostly found in two different age groups. The first one is between 15 and 35 years of age and the second one between 60 and 80 years.
Proving beneficial to the Crohn’s disease market is the various drug developments for treatment. Besides, changing lifestyles that has led to supplanting of healthy eating habits with unhealthy ones and rising in smoking are has resulted in more individuals being afflicted with Crohn’s disease, thereby stoking further growth in the market. In addition, increasing demand for biologics to cure bowel disorders, including Crohn’s disease, growing awareness about the health condition and the available treatments are also filliping the market.
Noticeable trends in the Crohn’s disease market are rising preference for symptomatic drugs and therapeutic over surgeries and emergence of better drugs in the market on account of considerable money being ploughed into research and development by manufacturers.

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Posing a challenge to the market, on the other hand, is the expensiveness of treatment. Further, lack of early diagnosis, mostly in developing countries, and the patent expiry of blockbuster drugs may hamper the expansion of the market in the near future.
From a geographical standpoint, North America is the leading region in the global Crohn’s disease market. The U.S. and Canada are mainly powering the growth in the region. Europe trails North America vis-à-vis market share. Asia Pacific is another attractive market that is slated to rise at a good clip.

Crohn's disease is a prolonged inflammatory disease of the bowel, affecting any part of the gastrointestinal tract, i.e. from the mouth to the anus. Crohn's disease is frequently diagnosed in two different age groups, first between 15 and 35 years old and second between 60 and 80 years old. The disease is mainly characterized by abdominal pain, diarrhea (with or without blood), fever, and weight loss. Additionally, extraintestinal conditions such as arthritis, erythema nodosum, and uveitis are detected among half of the patients. Prevalence and incidence of Crohn's disease is rising globally since the last few years. The exact cause of Crohn's disease is not recognized; however, some factors such as genetic malfunctions concerning the immune system concurrent with some environmental factors such as normal flora of human gut, smoke, foods, chemical contamination, or pollution triggers the occurrence of Crohn’s disease in susceptible people.

The global Crohn’s disease market is driven by increasing incidence of bowel disorders such as Crohn’s disease, leading to drug innovations for treatment. Crohn’s disease is more prevalent in developed and industrialized countries, particularly in individuals who smoke, and also with changing food habits, such as preference of fast food over vegetables and fruits. Therefore, rising patient population due to lifestyle changes and other factors also contributes to the expansion of the market. Furthermore, rising demand for biologics for treatment of bowel disorders such as Crohn’s disease, increasing awareness about Crohn’s disease, and the available treatments are estimated to propel the global market. Additionally, drug manufacturers are vigorously focusing on innovative products having more efficiency. Therefore, increased preference and utilization for anti-inflammatory drugs and biologics coupled with the rising acceptance of biosimilars is anticipated to play a significant role in boosting the Crohn’s disease market during the forecast period.

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Therefore, the Crohn’s disease market is projected to witness key trends such as increased preference for symptomatic drugs and therapeutic over surgeries, better disease management for inflammatory bowel diseases like Crohn’s disease, and the arrival of improved drugs in the market due to better investments in R&D programs, prevailing the market. However, high cost of treatment is likely to be a major restraint for the market. Moreover, lack of early diagnosis, mostly in developing countries, and the patent expiry of blockbuster drugs may hamper the expansion of the market in the near future.

The global Crohn’s disease market can be segmented into diagnosis, drug type, and region. Crohn’s disease can be diagnosed by blood test, colonoscopy, capsule endoscopy, sigmoidoscopy, small bowel imaging, double-balloon endoscopy, computerized tomography (CT), and magnetic resonance imaging (MRI). In terms of drug type, the market can be segmented into anti-diarrheal, antiinflammatory drugs, immuno suppressors, antibiotics, and pain relievers.
In terms of geography, the Crohn’s disease market can be segmented into North America, Europe, Latin America, Asia Pacific, and Middle East & Africa. North America dominates the global Crohn’s disease market. Major share of the region is attributed to the significant incidence of Crohn’s disease in the region, mainly Canada and the US (Ranjbar et. al. 2015), unhealthy life style including fast food consumption and smoking habits, progressive healthcare infrastructure and innovative healthcare solutions. Europe follows North America in terms of share of the global Crohn’s disease market. The Crohn’s disease market in Asia Pacific is projected to expand at a high growth rate. This rise is primarily due to changing food habits, industrialization, and innovative diagnostic and treatment options for the disease. Major players in the market find countries in Asia to be productive markets for Crohn’s disease with the increasing incidence of the disease in the countries in the region. They are making significant investments, which in turn is likely to fuel the expansion of the market in the region.

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Key players operating in the global Crohn’s disease market include AbbVie Inc., Allergan, Inc., Bayer AG, Bristol-Myers Squibb, Boehringer Ingelheim GmbH, F. Hoffmann-La Roche, Eli Lilly and Co., GlaxoSmithKline plc, Janssen Biotech, Inc., Johnson & Johnson, Novartis International AG, Pfizer Inc., Sanofi, and Takeda Pharmaceutical Company Limited.
The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

Veterinary Antiseptics Market is Envisaged to Hit US$401.6 mn by 2023

According to Transparency Market Research in its recent publication, Zoetis Inc., Merial, and Merck Animal Health – the three leading players in the Asia Pacific, Latin America, and Rest of the World veterinary antiseptics market had collectively taken up 46.3% of the market in 2014. Companies in this moderately consolidated market are expected to will pay more attention devising antiseptics for animals segment. Recent developments in cosmetic-based antiseptic products, including shampoos and skin lotions are expected to be strong game-changers for the veterinary antiseptics market and its players over the coming years.

The TMR report states that the Asia Pacific, Latin America, and Rest of the World veterinary antiseptics market was valued at US$243.0 mn in 2014. The market is expected to reach US$401.6 mn by the end of 2023, after expanding at a CAGR of 5.6% within a forecast period from 2015 to 2023. Asia Pacific is expected to take up a leading chunk of the overall demand volume in the market for the coming years, owing to swift healthcare industry evolution and a high urban population, in countries such as India and China. Based on products, iodophors and iodine are expected to continue enjoying a high demand volume over the coming years, despite the presence and development of substitutes.

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Growing Pet Adoptions and Meat Consumption Spurs Veterinary Antiseptics Demand

"One of the key factors driving the demand in the market for veterinary antiseptics is the growing number of pet owners in urban areas. The adoption rate for of animals in emerging economies is expanding at a swift pace, creating an overall incremental demand for pet care and veterinary products. “Pet ownership and rising disposable incomes have made their mark in the pet care markets as a growing number of pet owners are investing purchasing high quality animal care products, including antiseptics,” states a TMR analyst.
The rise in demand for meat, milk, eggs, and other animal and poultry products across Asia Pacific and Latin America is quite significant a factor to influence the demand for veterinary products and services in the animal husbandry industry of these regions. Rising disposable income is again a key driver for the veterinary antiseptics in the overall market as it allows for more consumers to purchase better quality meat and dairy products. The demand for veterinary antiseptics is bolstered further by the growing awareness among consumers regarding animal diseases and the need to buy products created from healthy animals. Thus, the rising expenditure on animal healthcare is creating a direct impact on the revenues of the Asia Pacific, Latin America, and Rest of the World veterinary antiseptics market.

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Highly Dynamic Regional Regulatory Profiles Hamper Overall Market

Country-specific regulatory guidelines, especially in countries such as Japan, have been hampering the growth of this market in the recent years. The long-drawn process of approval, despite the international approval of the product, has restrained the veterinary antiseptics market in these regions over the recent years. The overall market is also being hampered by the significant dip in the number of veterinarians across emerging economies. Poor career prospects for veterinarians in developing nations of India, China, and Brazil in the past few years is also anticipated to put a downward pressure on sales of veterinary antiseptics as the number of prescriptions will drop.
The information presented in this review is based on a Transparency Market Research report, titled, “Veterinary Antiseptics Market (Product - Iodine and Iodophors, Chlorhexidine, Alcohol, and Hydrogen peroxide; and Species - Bovine, Porcine, Ovine, Equine, Canine, Feline, and Camelidae) - Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015 - 2023.”

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Kidney Cancer Drugs Market to Report a CAGR of 6.6% by 2020

The global kidney cancer drugs market is dominated by a few global giants, namely F. Hoffmann-La Roche Ltd., Bayer AG, Novartis AG, GlaxoSmithKline plc, and Pfizer, Inc. This makes the competitive landscape highly consolidated in nature. Competition among the players is stiff too.
Biopharmaceutical behemoth Pfizer, Inc., among them, led the global market for kidney cancer drugs with maximum share in 2013 on the back of Sunitinib and Axitinib, two of the main drugs used for treating kidney cancer. Other big names in the industry, such as Novartis and GSK too are adopting other strategies to increase their geographical outreach. They are focusing on bolstering their distribution networks in the relatively underserved markets in the emerging nations that are seeing an increasing prevalence of kidney cancer cases.

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A report by Transparency Market Research predicts the global market for kidney cancer drugs to expand at a 6.6% CAGR during the period between 2014 and 2020.

North America Market Leads on the Back of Commercial Availability of Drugs from Prominent Brands

Depending upon the prominent brands of drugs, the global market for kidney cancer drugs can be segmented into Avastin (Bevacizumab), Afinitor (Everolimus), Inlyta (Axitinib), Torisel (Temsirolimus), Nexavar (Sorafenib), Sutent (Sunitinib), Proleukin (Aldesleukin/Interleukin-2), and Votrient (Pazopanib). Of them, Sutent, which is the marketed version of Sunitinib – Pfizer’s drug in the global kidney cancer drugs market, raked in maximum revenue in 2013. This is because Sutent is mainly prescribed as the first-line of treatment against kidney cancer. Sutent is also among the most studied drugs in its class for multiple indications, as it targets multiple receptor tyrosine kinases (RTKs).

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Geography-wise, the key segments of the global market for kidney cancer drugs are North America, Europe, Asia Pacific, and the Rest of the World (RoW). North America, among them, accounts for maximum market share owing to most prominent brands of kidney cancer treatment drugs being commercially available. In addition, a substantial number of patients and a solid healthcare system tailor-made for the pharmaceutical industry is also majorly fuelling the market in the region. North America accounted for 45% of market share in 2013.

Rising Population of Geriatrics Highly Susceptible to Kidney Cancer Driving Market

The global market for kidney cancer drugs is predicted to clock steady growth in the upcoming years because of an increasing geriatric population and higher prevalence of kidney cancer. As per the American Cancer Society, those afflicted with kidney cancer are mostly in the higher age bracket. The average age of people diagnosed with the malady is 64. Kidney cancer is very uncommon in people under the age of 45. The organization also finds that kidney cancer is one of the 10 most common cancers in both men and women.

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Approval of novel drug molecules is also serving to catalyze growth in the global kidney cancer drugs market. Posing a challenge to the market, on the contrary, is the growing sales of generic drug variants on account of expensiveness of branded cancer drugs.
A trend noticed in the global market for kidney cancer drugs is the manufacturers shifting their gaze towards developing economies to bring about sales growth.
This review is based on the findings of a TMR report, titled, “Kidney Cancer Drugs Market (Major Drugs: Afinitor (Everolimus), Avastin (Bevacizumab), Inlyta (Axitinib), Nexavar (Sorafenib), Proleukin (Aldesleukin), Sutent (Sunitinib), Torisel (Temsirolimus), Votrient (Pazopanib)) - Global Industry Analysis, Pipeline Analysis, Size, Share, Growth, Trends, and Forecast 2014 - 2020.”

Dilated Cardiomyopathy Therapeutics Market is Envisaged to Hit US$328.6 mn by 2020

Transparency Market Research in a recent publication says competition in the global dilated cardiomyopathy therapeutics market is expected to grow as prominent companies strive to develop effective drugs for the treatment of dilated cardiomyopathy. For example, in February 2017, Myokardia Inc., a biopharmaceutical company, announced first time administer of MYK-491 to a batch of healthy subjects. MYK-491 is a treatment for dilated cardiomyopathy which is in Phase 1.
Keen players in the market are also focusing on collaborations, mergers, and acquisitions to consolidate their position. For example, in January 2015, Array BioPharma announced its plans of acquiring and obtaining world rights to encorafenib, which is a late stage oncology product from Novartis Pharma AG.

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As per estimates by Transparency Market Research, the global dilated cardiomyopathy therapeutics market will be worth US$328.6 mn by the end of 2020 vis-à-vis revenue, expanding at a CAGR of 4.6% from 2014 to 2020.

Growing Incidence of Cardiac Diseases to Catapult Asia Pacific to Lead Position

The segment of angiotensin II receptor blockers led amongst other drug class segments in 2013. This was followed by the segment of beta blockers. The high acceptance of angiotensin II receptor blocks is attributed to their effective therapeutic action for the treatment of dilated cardiomyopathy.
Geography-wise, the report segments the global dilated cardiomyopathy therapeutics market into: North America, Asia Pacific, Europe, and Rest of the World. North America stood as the leading regional market in 2013 mainly due to high incidence of cardiac diseases. Asia Pacific is expected to take the lead in the upcoming years as changing lifestyle resulting in increasing incidence of cardiac diseases propels growth of dilated cardiomyopathy therapeutics market.

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Efforts to Develop Specific Drugs for Dilated Cardiomyopathy Propels Growth
The alarming rise in the prevalence of congestive heart failure is one of the prominent growth drivers of the global dilated cardiomyopathy market. Dilated cardiomyopathy accounts for 30-40% of total number of congestive heart failures each year. As per statistics of the World Health Organization, 17.5 million deaths in 2013 were related to heart disorders. The increasing incidence of congestive heart diseases has created an urgent need for effective drugs and treatment, thereby benefitting the dilated cardiomyopathy therapeutics market.

Due to this, several companies have initiated to carry out clinical trials so as to develop drugs specifically for dilated cardiomyopathy. At present, there is not a single FDA approved drug specifically for dilated cardiomyopathy because of which treatment administered is the same as that for congestive heart failure. For example, Array BioPharma is carrying out phase II study for its drug ARRY-371797 for the treatment of dilated cardiomyopathy. In addition, in 2014, Celladon Corporation completed its phase II study of MYDICAR to be used for the treatment of dilated cardiomyopathy. Success of these clinical trials will positively influence the global dilated cardiomyopathy therapeutics market.

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Studies reveal that angiotensin receptor blockers such as valsartan can reduce probability of hospitalization by 28%. These drugs have also been effective for patients of systolic heart disease by reduction of deaths by 37% and also for reduced frequency of hospitalization. These factors are furthering the expansion of the global dilated cardiomyopathy therapeutics market.
On the flip side, the side effects of dilated cardiomyopathy therapeutics is leading to their declined use. Moreover, availability of implantable devices and promising gene therapy are acting as roadblocks to the market.

Meningococcal Vaccines Market is expected to be worth USD 4,450.4 million up to 2022

Routine Vaccination Programs to Boost the Commercial Success for Meningococcal Vaccines Market
The meningococcal disease is triggered mainly due to environmental factors and low immunity. The effect and the rise in the incidence is totally dependent on the age, geographical location, and time. These factors can have either subtle or adverse effects on the patients accordingly. Increased prevalence of disease and rising awareness about its prevention through vaccinations are one of the major driving factors for the growth in the market. Moreover, various organizations all over the world are also taking initiatives by conducting vaccinations and disease awareness drives, for example fundraising events, and summits to educate the masses about the disease and ways to prevent it. These awareness measures will also propel the usage of meningococcal vaccines that in turn will boost the market growth.

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Between 2014 and 2022, the global meningococcal vaccines market is estimated to progress at a CAGR of 12.40% to reach a value of USD 4.450.4 million by 2022. Asia-Pacific is expected to grow at a good pace in coming times. The significant improvement in the regional market is will be supported by the governments with awareness programs and immunization campaigns.
Advent of advanced serotype B vaccinations from huge worldwide drug makers, for example, Novartis and Pfizer, are acting as the major driving force behind the meningococcal vaccines. The mandate of vaccination programs across the globe has immensely benefited the global market in recent times. Increment in subsidizing from the legislature of compulsory vaccinations during childbirth will likewise lessen expensive and unaffordable costs of patients and rise in moderate access to meningitis vaccines. The disease is common among people suffering from asplenia, infants, and adolescents, with a rising mortality and morbidity rate. So, because of this high occurrence of meningococcal infection every year, it is probably going to empower utilization of the vaccine. Even the government is also coming up with various educative and awareness program for school children.

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Cost Wars and Increasing Financial Austerity Hampers the Meningococcal Vaccines Market
The prime hindrances of the market incorporate cost wars for the vaccines from similar kind of drug makers that may wipe out a more noteworthy client base and diminish general scope of customers. Although the polysaccharide vaccines were the initial ones to be used in treating the disease, but its usage declined due to its low immunity in infants, the inability to produce proper immunologic memory response, and being over-responsive in case of repeated doses. The other hindrance incorporates expanding money related severity in the European countries, which is expected to hamper the R&D base for the antibodies. Further, serotype mismatch and no proper coverage over nations is probably going to contrarily influence the demand for the vaccines. Moreover, due to late evaluation of the disease on regular basis because of low cost-effectiveness may adversely affect the market for meningococcal vaccines over the long haul in the developing countries.
Nevertheless, due to prominence of prevention modes, along with the attempts to overcome the drawbacks, the combination vaccines segment is anticipated to grow rapidly. These vaccination with organisms such as Haemophilus influenza type B, also fuels the increase in growth for meningococcal vaccines.

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Competition in the global meningococcal vaccines market is speculated to escalate due to rise in local manufacturing, states Transparency Market Research (TMR) in a research report. The meningococcal vaccines market is immensely competitive with several big and small vendors. Vendors are going into strategic tie-ups to encourage and produce drugs. GSK, Sanofi, and Pfizer are some of the leading players in the meningococcal vaccines market. In recent times, the innovative solutions and its implementation through huge campaigns and programs in different regions such as sub-Saharan Africa, has reduced the meningococcal from spreading further. Apart this, various manufacturers are moving their base to developing economies to explore the scope of better business environment in those regions. Countries like China, and India are the main target for the investors to establish their developmental hub, due to the availability of cheap manpower, skilled labors, comparatively low manufacturing cost.

Home Rehabilitation Products and Services Market is Envisaged to Hit US$176.1 bn by 2023

According to a research report recently published by Transparency Market Research, mergers and acquisitions are likely to be a core aspect of the expansion plans carried out by the leading players in the global home rehabilitation products and services market. Some of the leading players in the market for 2014 included RehabCare, Stryker Corporation, Medline Industries, Prism Medical, DJO Global, and AliMed, all who shared the commonly popular tendency of going through mergers and acquisitions. The report also states that a large number of key strategies employed by newer entrants to the market are focused on renting rehabilitation products rather than purchasing them, while players are also forming collaborative agreements with healthcare providers.

According to the TMR report, the global home rehabilitation products and services market is slated to expand at a CAGR of 8.50% from 2015 to 2023. The market was calculated at US$84.2 bn in 2014 and is expected to reach US$176.1 bn by the end of 2023.

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APAC Demand for Home Rehabilitation Products and Services to Surge

North America took up the leading share in the held the largest share in the global home rehabilitation products and services market for 2014, driven by a large elderly population percentage suffering from chronic diseases and a growing number of available surgical procedures in a highly advanced healthcare industry. Over time, Asia Pacific will be showing a much higher growth rate in its demand for home rehabilitation products and services, owing to an increasing count of patients suffering from strokes, mobility-related conditions, neck and back pain-related conditions, and burn injuries.
Wheelchairs led the global home rehabilitation products and services market in 2014 based on products, owing to the rising incidence of disabilities and rising global aging population. Based on services, the market was dominated by the demand for physical therapy due to factors such as the increasing financial ability of the elderly to treat conditions such as osteoporosis, arthritis, and hip and joint surgeries and replacements.

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Increasing Geriatric Patient Count Propels Market Demand

“The global home rehabilitation products and services market is currently being driven by the growing prevalence of chronic diseases. The spike in chronic illness cases is directly proportional to the staggering rise in the geriatric population, as the baby boomer era comes to a close. This is creating a shift in core demographics for the healthcare industry and is expected to further fuel the need for home rehabilitation products and services over the coming years,” states a TMR analyst. As stated before by the U.S. Census Bureau, 76.4 mn baby boomers were present in the U.S. in 2014. This is a massive consumer base for the healthcare industry and is creating the need for several specializations in healthcare, especially in home healthcare areas.
The future of the global home rehabilitation products and services market is also likely to show a positive growth rate, owing to the advancements in the healthcare industry that are leading to a lower mortality rate among the elderly. Emerging economies are also expected to increase their demand for home rehabilitation products and services due to the swiftly expanding healthcare infrastructure in these regions and growing medical outreach towards remote areas.

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High Costs Continue to Hamper Market Growth

The global home rehabilitation products and services market is highly unorganized, fragmented, and competitive, creating current market stagnation and paving way for future growth opportunities for existing players as well as new entrants. However high cost of the rehabilitation services, and lack of appropriate health insurance schemes in developing nations is anticipated to pull back the growth of home rehabilitation products and services market.

Blood Coagulation Factor Market Projected to Witness Vigorous Expansion by 2025

The capability of our body cells to cease blood loss following a vascular injury by forming blood clot is vital to sustain health. Coagulation or clotting is the process of converting the liquid blood into a gel like clot to cease bleeding. A number of coagulation or clotting factors are involved in the route that leads to the physiological procedure called hemostasis. Hemostasis is the mechanism of clotting involving activation, adhesion, and aggregation of platelets mediated by a number of clotting factors eventually leading to repairing of the injured tissue. Any problem or absence of any of these factors can potentially lead to a rare but serious blood clotting disease and excessive bleeding. Some of the major coagulation factor disorders are the hemophilias and Von Willebrand disease.

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The global blood coagulation factor market is anticipated to grow at a rapid pace owing to a multitude of factors. Blood coagulation factors falls under the infusible hemostats category. Developments in hemostasis technology has led to improvement of wide range of products that have enabled clinicians to provide proper emergency assistance to hemophilia patients. Factor VIII is a vital blood clotting protein in the human body. Its deficiency caused by a genetic defect results in a bleeding disorder called hemophilia A. Factor VIII concentrates are obtained from human plasma or via recombinant DNA technology to treat patients with hemophilia A. These factor therapies are infused intravenously through a vein in the arm or a port in the chest. Increase in the global trauma and accident cases is another driver of the blood coagulation factor market. Growth in the diagnosis rate of blood clotting diseases such as hemophilia and Von Willebrand disease is also expected to drive the global blood coagulation factor market during the forecast period. According to the data by published The Centers for Disease Control and Prevention (CDC), the incidence rate of hemophilia in the U. S. is 1 in every 5,000 male births. Von Willebrand disease (VWD), another bleeding disorder, is the most commonly occurring blood disorder that affects 1% of the population of the U.S. 1 in every 100 (almost 3.2 million) people in the U.S. is suffering from Von Willebrand disease (VWD). Huge number of patients with bleeding disorders increase the need for blood coagulation factor. Factor concentrates offer the most promising treatment results in these diseases. However, stringent regulatory policies and shortage in plasma supply can hamper the market growth during the forecast period.

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In terms of geography, the global blood coagulation factor market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is projected to remain the dominant markets for blood coagulation factor market due to the high yield of plasma products, advancements in technology, and increasing number of patients with blood disorders. Asia Pacific is expected to expand at a high CAGR owing to the strong economic growth, increase in the disposable income, rise in the health care infrastructure, and growing investments by market players in this region. India has the highest number of hemophilia patients in the worlds. According to the Indian Genetic Disorder Database, there were an estimated 55,000 hemophilia patients in India in 2015, of these 60% to 70% remain undetected. Moreover, the birth rate hemophilia in India is 32 per 1,000 births. Huge number of patients with bleeding disorders in the country is expected to offer large opportunities in the blood coagulation factor market in India.
Key players operating in the global blood coagulation factor market include Baxter International Inc, CSL Ltd., Inc., Grifols International SA, Kedrion S.P.A., Novo Nordisk A/S, and Octapharma AG.

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The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

Urine Sediment Analyzers Market to Record Ascending Growth by 2025

Urine sediment analysis is a method to predict the health status of renal and genitourinary functions. Urine analysis is one of the most commonly performed diagnostic procedure in clinical practices to detect the presence of chronic diseases. Urine sediment refers to substances such as bacteria, mucus, salt (calcium oxalate), calcium carbonate, magnesium phosphate and calcium phosphate, protein, and amino acid. The urine sediment can be obtained by centrifuging the urine sample using centrifuge equipment. Diverse medical conditions diagnosed with the help of urine sediment analysis are urinary tract infections, presence of kidney stones, and other metabolic disorders such as diabetes. Conventional urine sediment analysis methods such as analysis under coverslip or in a chamber are hectic, uncertain, and time consuming procedures. Moreover, manual urine analysis requires well-trained and experienced staff. The automation of technology in the urine sediment analyzers has helped in the reduction of time and labor required for urine sediment analysis. Image-based automated urine sediment analyzers are able to isolate, identify, and characterize particles on the screen. Hence, the increasing adoption of automatic urine sediment analyzers is propelling the market growth of urine sediment analyzers. Technological innovations are creating new market opportunities for key players. However, high cost of automatic urine sediment analyzers is restricting the growth of the global urine sediment analyzers market.

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The global urine sediment analyzers market is segmented based on product type, application, end-user, and region. In terms of product type, the market is categorized into fully automatic urine sediment analyzers and semiautomatic urine sediment analyzers. The fully automatic urine sediment analyzers segment is further classified into microscopic urine sediment analyzers and flow-cytometric urine sediment analyzers. In terms of application, the market is classified into urinary tract infections, diabetes, kidney diseases, hypertension, and others. The urinary tract infections segment dominates the global urine sediment analyzers market. However, the diabetes segment is expected to expand at a high CAGR during the forecast period owing to increasing incidence of diabetes especially in countries such as Asia Pacific, and the Middle East & Africa. In terms of end-user, the market is segmented into hospitals, diagnostic centers, and clinical pathological laboratories. The diagnostic centers and clinical pathology laboratories segments are expected to hold major share of the global market for urine sediment analyzers during the forecast period owing to increasing number of tests performed in the clinical and pathology laboratories.

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Geographically, the global urine sediment analyzers market is classified into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominates the global market owing to growing incidence of renal disorders, rising prevalence of diabetes, increasing per capita health care spending, and growing adoption of new and advanced technologies in the U.S. Europe is the second largest market for urine sediment analyzers. Asia Pacific is considered as an emerging market, especially the emerging economies of the region such as China, India, and Japan, owing to the increasing number of diagnostic centers and pathological laboratories, growing medical tourism, and rising health care awareness among the people.

Key players operating in the global urine sediment analyzers market include Beckman Coulter, Inc., Roche Diagnostics, Bio-Rad Laboratories, Inc., DIRUI.com.cn., 77 Elektronika Kft., Bayer AG, A. Menarini Diagnostics S.r.l., Sysmex Corporation, URIT Medical, ARKRAY, IDEXX Laboratories, Inc., and Xuzhou Dongjiu Electronic Technology Co., Ltd. The key strategies adopted by leading market players are mergers and acquisitions, partnerships, and collaboration with the related organizations to increase their business. For instance, in 2010, Sysmex Corporation and ARKRAY collaborated to develop a fully automated and integrated urine analyzer, which combines both urine chemistry and sediment analysis in a single instrument.

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The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

Inhalation Systems Market to Witness Widespread Expansion During 2017 - 2025

The inhalation therapy had been practiced by ancient civilizations in Egypt, India, Greece, and China. Proven records of use of the therapy for thousands of years are available. In order to resolve respiratory issues, the pulmonary method of administration has been effective in terms of confined and systemic supply of several drugs and biopharmaceuticals. The only reason for the lack of desired outcome or an unfavorable effect is inappropriate utilization of devices and improper training for handling of devices. At present, inhalation therapy is considered the best solution for lung diseases such as chronic obstructive pulmonary disease (COPD), asthma, and cystic fibrosis. The therapy permits the use of smaller doses and reduces systemic side-effects. Chronic obstructive pulmonary disease (COPD) is ranked by the World Health Organization (WHO) as one of the most prevalent long-term conditions in the world. The global burden of COPD is projected to rise in the near future, particularly in developing countries, due to increasing elderly population, growing habit of smoking, and rising pollution. Rising incidence of pulmonary diseases across the globe is a major factor fueling the global inhalation systems market.

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The global inhalation systems market is primarily driven by rising prevalence of COPD, asthma, and chronic respiratory diseases; growing geriatric population facing chronic respiratory problems; and changing lifestyle. Moreover, introduction of novel and advanced pulmonary devices in customized shapes and sizes, availability of auto-injectors, and rise in research and developmental activities by pharmaceutical and biotechnology companies in order to develop novel oral and nasal drug formulations are some of the other important factors likely to drive the market from 2017 to 2025. However, complications and side-effects associated with drug inhalation, unavailability of a single effective inhaler device that can treat multiple disease indications, and lack of awareness are other factors restraining the market. Health care at home, campaigning by manufacturers and hospitals to increase awareness about respiratory diseases, and technological advancements are the current trends in the market for inhalation systems.

The global inhalation systems market has been segmented based on product, disease indication, end-user, and geography. Based on product, the market has been segmented into inhalers, nebulizers, nasal sprays, and others. The inhalers segment has been sub-divided into dry powder inhalers (DPIs), metered dose inhalers (MDIs), and multi-dose liquid inhalers. The nebulizers segment has been sub-segmented into ultrasonic nebulizers, compressed air-jet nebulizers, mesh nebulizers, and others. In terms of revenue, the inhalers segment is anticipated to hold a major share of the global inhalation systems market by 2025. It is expected to dominate the market from 2017 to 2025.

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In terms of disease indication, the global inhalation systems market has been divided into asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, anesthesia, nasal congestion, and others. According to a study conducted by the World Health Organization (WHO), chronic obstructive pulmonary disease was found to be the fifth cause of deaths globally in 2002 and is projected to be the fourth cause of mortality by 2030. Moreover, according to the WHO estimates, 65 million people have moderate to severe COPD. More than 3 million people died of COPD in 2005, which equaled to 5% of all deaths worldwide. Rising awareness about COPD and technological advancements in product offerings are major factors expected to fuel the COPD segment during the forecast period.

Based on end-user, the global inhalation systems market has been segmented into hospitals & clinics, ambulatory surgery centers, home care centers, and others. Among these, the home care centers segment is expected to register the maximum growth rate during the forecast period, owing to rising geriatric population, increasing per capita expenditure, and growing awareness about respiratory diseases. A survey conducted by the Healthcare First organization concludes that more than 3.4 million people in the U.S. receive Medicare skilled home health care services, due to rising elderly population and increasing incidence of chronic health conditions in the country. Geographically, the global inhalation systems market has been classified into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is anticipated to dominate the global market in the near future. The market in the region is likely to witness significant growth during the forecast period, owing to affordability of advanced products and rising prevalence of lifestyle-related diseases.

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Key players operating in the global inhalation systems market are 3M, Boehringer Ingelheim GmbH, AptarGroup, Inc., Koninklijke Philips N.V., PARI GmbH, Trudell Medical International, Teleflex Incorporated, INSPIRO Medical Ltd., ALEXZA, and Monaghan Medical Corporation.
The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

Human Papillomavirus (HPV) Vaccine Market Projected to Witness Vigorous Expansion by 2025

Human papillomavirus (HPV) is a cluster of additional 150 related viruses. Each human papillomavirus virus in this big cluster gives a number that is termed as its HPV type. HPV is termed for the growth (papillomas) of certain HPV types which can cause. HPV contagions cause almost all types of cervical cancers and is the second most common cause of death in women due to cancer globally. Around 10 million cancer cases, diagnosed every year around the world and out of this 10 million cases about more than 15% are due to contagious agents. Infection by HPVs accounts for around 30% of tumors (around 5% of all type of cancers), with helicobacter pylori, hepatitis C, and hepatitis B viruses collectively account for additional 60% cases of cancers owing to contagious etiology.

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HPVs infect the stratified flattened epithelial cells of mucous and skin membranes, which cause benign injuries, some of HPVs have the potential to develop to invasive cancer. HPVs are non-enveloped, minor viruses having about 8 kb spherical genome codes two essential proteins such as L1 & L2 that form several nonstructural proteins, and viral capsid that are significant for the life cycle of human papillomavirus however not combined into virions. Among all type of cancers caused by the HPV infection, cervical cancer is a major type of cancer that accounts around 10% cancer cases of several other type of cancer in women globally. It is the second most common cause of death caused due to cancer, after breast cancers, among women. Time between HPV infection and malignant development usually minimum 10 years and is normally longer. Cervical cancer is uncommon among women under the age of 25 years. The incidence rate increases progressively among women of more than 25 years of age. Incidence rate is the highest in women over 40 years of age. Approximately 80% of cervical cancers have been observed in under developed countries, owing to the lack of sufficient resources for high-quality screening programs for this cancer, which identify cervical defects via testing for the presence of cervical HPV DNA or by Pap smear testing.

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According to WHO report 2017, in year 2006, world’s first prophylactic vaccine (quadrivalent vaccine) for immunization against human papillomavirus (HPV) became available. The global HPV vaccines market is now well-established; however, coverage rates of vaccines among the traditional target population of teenage girls remains persistently low. Primarily, HPV vaccines were developed and promoted to prevent cervical cancer. Stronger support from both non-government and government organizations, such as UNICEF and WHO, development of novel vaccines with improved effectiveness, safety, and easy availability of vaccines are anticipate to drive the global HPV vaccines market in the near future. Furthermore, technological improvements in the molecular genetics field is likely to boost the human papillomavirus vaccines market. However, high cost of treatment and lack of awareness among people are factors restraining the market.
The global human papillomavirus vaccine market can be segmented based on product type, end-user, and geography. In terms of product type, the market can be classified into inactivated vaccine, attenuated vaccine, and others (subunit vaccines, DNA vaccines, toxoid vaccines, conjugated vaccines, etc.). Based on end-user, the global human papillomavirus vaccine market can be categorized into hospital, scientific research, and others. In terms of geography, the market can be divided North America, Asia Pacific, Europe, Latin America, and Middle East & Africa. North America dominated the global market due to technical advancement, increased research & development operations for the vaccine development, and awareness among people. Additionally, the development of advance diagnostic tests are a major factor driving the market in this region.

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Key players in the global human papillomavirus vaccine market include Sanofi SA, Pfizer Inc., Merck & Co., Inc., MedImmune, Janssen Pharmaceuticals, Inc., Hualan Biological Engineering Inc., GlaxoSmithKline Plc., Bharat Biotech International Limited, Abelló A/S, Altimmune, Inc., Bavarian Nordic A/S, and BiondVax Pharmaceuticals Ltd.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.