Thursday 28 December 2017

Industrial Enzymes Market foreseen to grow exponentially by 2020

Industrial enzymes are molecules or complex proteins that help in catalysis of biochemical reactions. Industrial enzymes have the characteristics of reducing the energy consumption of a reaction without being consumed in the reaction. On the basis of product type, industrial enzymes market can be segmented as lipase, carbohydrase and protease. On the basis of its applications, industrial enzymes market is segmented into four segments including food & beverages, bio fuel, cleaning agents and other applications including animal feed. Food & beverages is the most dominant application segment for industrial enzymes and this trend is anticipated to continue for a foreseeable future.

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Enzymes are produced by living cells and industrial enzymes market can be segregated into three segments on the basis of the source namely microorganisms, animals and plants. Fermentation is the most dominant process used for the production of industrial enzymes. Microorganisms such as yeast and bacteria among others are employed in the fermentation process. Solid state fermentation and submerged fermentation are dominant fermentation process used in enzymes production. Submerged fermentation involves a liquid medium for enzyme production and solid state fermentation employs a solid substrate for the production. Centrifugation or lysing process is used for extraction of enzymes produced extracellularly or intracellularly by the microorganism.

Major portion of the global production of industrial enzymes is employed in the production of food & beverages including cheese, bread and alcohol among several others. Increasing demand for packaged food & beverages have led to high growth in food & beverages application segment that has been among foremost factors driving demand for industrial enzymes. There has been a surge in government incentives and benefits to promote the use of bio fuel as a substitute for the conventional non renewable sources of energy. Increasing demand for bio fuel primarily driven by the surge in government incentives and the environmental benefits associated with bio fuel is anticipated to be among major factors driving demand for industrial enzymes in the near future. Research and development activities to increase the application scope of industrial enzymes are anticipated to offer huge growth opportunity for market growth.

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North America followed by Europe dominates the global demand for industrial enzymes. Moreover, market shares of North America and Europe are anticipated to decline in the near future primarily owing to relatively high growth in Asia Pacific and RoW region. Increasing demand for bio fuel is expected to be foremost factors driving demand for industrial enzymes in North America and Europe. Asia Pacific is the third largest market for industrial enzymes. Moreover, Asia Pacific comprises two of the largest countries in terms of population, India and China leading to huge demand for food & beverages in the region. Furthermore, high GDP growth and increasing disposable income in the emerging economies of Asia Pacific is expected to drive demand for industrial enzymes in the region. Owing to aforementioned factors, Asia Pacific is anticipated to be the fastest growing geographic segment for industrial enzymes during the forecast period. High growth in developing economies of South America and Africa are anticipated to offer huge growth opportunity for industrial enzymes in the near future.

Some of the key players in industrial enzymes market include Amano Enzyme Inc., Novozymes, BASF SE, Dyadic International Inc., E. I. du Pont de Nemours and Company, Codexis Inc. and The Soufflet Group among others.

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Autologus Tissue Repair Market foreseen to grow exponentially over 2016 – 2024

Global Autologous Tissue Repair Market: Overview

The growing therapeutic applications of regenerative medicines has made a mark in the area of wound care such as those in refractory injuries and chronic wounds. With rapid advances in regenerative medicines, stem cells have gained increased popularity across autologous tissue engineering methods. Apart from wide applications in surgical medicine, the evolution of the market has influenced multiple clinical areas such as cardiovascular medicines, refractory wound care, and orthopedics. Prominent clinical applications of autologous tissue repair include bone repair, cardiac repair, neural repair, skeletal muscle repair, and pediatric vascular conduits.

Technological advances have led researchers and clinicians in isolating, purifying, and re-injecting patient’s cells in refractory injuries with significant reliability and efficacy. In recent years, autologous tissue repair methods have emerged to be highly promising in abdominal wall reconstruction associated with chronic infections. These are mainly caused by intra-abdominal catastrophes and due to several technical constraints are difficult to close.

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The report offers in-depth insights into the key drivers and restraints, notable trends and emerging applications, technological advancements, market share and size of various segments, and competitive landscapes. The insights offered in the study are useful in evaluating lucrative avenues across various regions.

Global Autologous Tissue Repair Market: Trends and Opportunities

The growing prevalence of intractable ailments in a rapidly increasing geriatric populations across various regions and the increasing number of road accidents are the key factors driving the analogous tissue repair market. In addition, the growing prominence of autologous tissue repair therapies in chronic wound care and orthopedics has boosted the autologous tissue repair market. The increasing adoption of components separation technique (CST) for autologous repair of abdominal wall defects is anticipated to catalyze the market growth.

A growing number of therapeutic autologous therapies can also be accessed using point-of-care setting, thereby accentuating the autologous tissue repair market. However, the high cost of availing autologous tissue repair therapies is likely to hinder the market to an extent. In addition, strict regulatory compliance for the approval of these therapies has impeded the growth of the market in various regions. Nevertheless, recent progress in stem cell-based tissue engineering has further expanded the autologous approaches to tissue engineering. For instance, recent research in intervertebral disc regeneration shows that stem cells can be used to treat slipped discs. Furthermore, the growing popularity of multipotent stem cells is expected to accentuate the autologous tissue repair market. Clinical studies on improving the efficacy of CST and other similar methods are expected to create exciting opportunities in the coming years.

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Global Autologous Tissue Repair Market: Regional Outlook

North America is a prominent market for the autologous tissue repair market. The substantial growth of this regional market is attributed to the large scale presence of several players in the region. Europe is another prominent regional market and the extensive demand for autologous tissue repair is propelled by a large chunk of elderly population.

Asia Pacific is expected to grow at an impressive pace. The impressive growth of the market is driven by advances in healthcare infrastructure, frequent innovative product launches, and the swift pace of industrialization rate in emerging countries in the region. A major chunk of the demand is expected to come from countries such as India, Japan, Malaysia, and China.

Global Autologous Tissue Repair Market: Companies mentioned in the report

Some of the prominent companies operating in the autologous tissue repair market are Vericel Corporation, Matricel GmbH, and Orthocell Limited. Several companies are launching innovative products and entering into partnerships to consolidate their shares across major regions.

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Wednesday 27 December 2017

Latex Medical Disposables Market: Emerging Growth Factors and Forecasts 2024

Global Latex Medical Disposables Market: Snapshot
Latex medical disposables such as latex gloves are used during surgeries and check-ups. The demand for latex medical disposables is therefore quite high among doctors, surgeons, and dentists across the globe. Primarily, there are two types of latex gloves available in the market. These are powdered and non-powdered latex gloves. The non-powdered gloves might witness relatively more demand when compared with powdered gloves, as powdered gloves were found to be hindering the healing process of patients.
The market might encounter obstacles owing to the prevalence of latex allergies that induce several healthcare professionals to use non-latex products instead. Moreover, with the intensifying competition, the market players might have to bring down the prices of their products. As a result, sluggish growth in revenue might restrict the growth of the global market for latex medical disposables. However, the impact of these restraints will be negated by the emergence of novel technologies.

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The global market for latex medical disposables was pegged at US$4.1bn in 2015, and is expected to rise up to achieve US$6.4bn by the end of 2024, expanding at a CAGR of 4.9%.
Rising Demand from Countries in Asia Pacific to Accelerate Growth

Based on geography, the global latex medical disposables market has been segmented into Europe, Asia pacific, Latin America, the Middle East and Africa, and North America. The global latex medical disposables market is presently dominated by North America, which accounted for a 33% share of the global market during 2016, with Europe close-by at its heels. The increasing concerns about safety, growing awareness about health and the spread of contagious diseases, and increasing measures for preventing the spread of these diseases are some of the major factors driving the the market in Europe and North America.
Asia Pacific is also slated for substantial growth during the forecast period, expanding at a promising CAGR of 5.8% between 2016 and 2024. The countries in Asia Pacific such as India, Japan, Singapore, China, Australia, and Thailand are likely to represent a significant portion of the global market for latex medical disposables over the coming years. The growth of these regions can be attributed to the growing awareness about the safety of patients and healthcare professionals, rising per capita incomes of people, increasing healthcare expenditures of governments, and flourishing medical and pharmaceutical sectors in these regions.

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Latex Gloves Emerge as Dominant Product Segment

By product, the global market for latex medical disposables has been segmented into latex, foley catheters, latex gloves, urine bags, latex probe covers, and others. Hospitals, clinics, ambulatory surgical centers, diagnostic centers, and others are the key segments by end user. Of these, latex gloves have been witnessing increasing demand over the past few years. As a result, these products have been dominating the global market. In terms of revenue, this product segment accounted for nearly 60.4% of the global market for latex medical disposables during 2015. Latex gloves might continue to hold the foremost position as these gloves are an easy and effective way of protecting the hands of patients and healthcare providers from the risk of infection.

By end user, the hospitals segment dominated the global market for latex medical disposables in terms of revenue during 2015. The increasing number of surgical procedures and check-ups in hospitals, coupled with establishment of new clinics and hospitals is responsible for the dominance of this segment. This segment is slated to contribute 28.7% to the global market for latex medical disposables by the end of 2024. The diagnostic centers segment might hold the second-most position over the forecast period.

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Some of the major companies operating in the global market for latex medical disposables are Hartalega Holdings Bhd., Supermax Corporation Berhad, B. Braun Melsungen, C.R. Bard, Ansell, Top Glove Corporation, Dynarex Corporation, and Medtronic plc.

Radiopharmaceutical Market Size to Escalate at the Healthy CAGR during 2016 - 2024

The global radiopharmaceutical market was valued at US$4.7 bn in 2015 and is estimated to reach US$7.4 bn by 2024, expanding at a CAGR of 5.3% from 2016 to 2024.

Nuclear Reactors Emerge as Key Source of Radiopharmaceuticals

By radioisotope, technetium-99 held the major share in the global radiopharmaceuticals market, accounting for 50.3% in 2016. The 18F segment, on the other hand, is projected to expand at a 5.5% CAGR from 2016 to 2024, higher than any other radioisotope.

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Based on source, nuclear reactors lead the overall market in terms of revenue and the segment is also poised to exhibit a strong growth rate through 2024. Accounting for the dominant share in the radiopharmaceuticals market by end use, hospitals are likely to contribute significantly toward the growth of this market in the coming years. The others segment, which covers laboratories and universities, is anticipated to expand at the fastest pace despite being restricted to only the MEA and Asia Pacific regions.

Based on application, oncology took the lead owing to the growing use of various radioisotopes in the treatment of different cancers. On the basis of geography, North America is the clear leader and is slated to achieve a 60.3% share in the global radiopharmaceuticals market by 2024. Asia Pacific, on the other hand, will register a 6.3% CAGR from 2016 to 2024, emerging as the fastest expanding regional market in terms of revenue.

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Rising Incidence of Chronic Diseases Propelling Demand for Radiopharmaceuticals

The growing incidence of cancer and cardiovascular diseases – brought on by the rise in aging population, unhealthy food habits, prevalence of obesity – is one of the primary factors driving the radiopharmaceuticals market.

“The rising incidence of chronic diseases translates into the demand for diagnostic tests such as SPECT and PET, two of the latest systems used for the treatment of various cardiovascular and neurological diseases as well as cancer,” the TMR analyst states. According to the American Nuclear Society, 90% of the radioisotopes produced is used in gamma cameras or PET scan nuclear diagnostics. The remaining 10% is used in radioactive therapeutics drugs. This growing demand for diagnostic tests has a positive impact on the demand for radioisotopes and radiopharmaceuticals.
In addition to this, the rapid advancement in radiotracers and surging awareness regarding the effectiveness of radiopharmaceuticals will support the growth of the global market. On the other hand, stringent regulatory guidelines, a shortage in the supply of radioisotopes, and a shorter half-life of radiopharmaceuticals acts as impediments for the market.

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The radiopharmaceutical market is highly consolidated, wherein the top two players – Siemens Healthineers and GE Healthcare – jointly accounted for over 70% of the global market in 2015. Transparency Market Research has observed that the degree of competition is rather high in the market owing to the presence of key players with the availability of advanced technologies and potential productive sources and a high product manufacturing capacity.
“Acquisitions play an important role among established organizations because they support sales, product development, and new methods of production,” the author of the report finds. An excellent example would be AAA. The company acquired GE Healthcare S.r.L’s FDG-PET business as well as the 100% shares of Imaging Equipment Ltd. (IEL) in 2014. These moves have enabled the company in strengthening its presence across Italy, the U.K., and Ireland.

Intravenous Immunoglobulin Market value projected to expand by 2016-2024

The global intravenous immunoglobulin (IVIG) market is largely consolidated, with top four players: Grifols S.A., CSL Behring LLC, Baxalta Incorporated, and Octapharma AG, accounting for over 70% of the overall market in 2015. Grifols S.A. accounted for the dominant share of 23.0%, chiefly on account of the company’s strong geographic penetration.

Oligopoly in the market has led to intense competition among top players and has compelled companies to take course of strategic mergers and acquisitions and geographic expansions. Point in case is the CSL Behring LLC’s geographic expansion by opening operations in Russia in December 2015. The company stated that the expansion was driven by large unmet need of quality biotherapeutics and blood plasma products in the country.

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Transparency Market Research estimates that the global intravenous immunoglobulin (IVIG) market, which was valued at US$7.23 bn in 2015, is projected to expand at a CAGR of 8.5% from 2016 to 2024 and reach US$14.92 bn in 2024. In terms of end users, the hospitals segment is presently leading, accounting for a more than 62% of the overall market in 2015. The segment is, however, expected to lose prominence to the home care segment and reflect a loss in its overall share by 2024. In terms of geography, North America, which presently accounts for over 45% of the global market, is expected to retain dominance by 2024 as well.

Rising Prevalence of Neurological Diseases to Boost Global Demand for IVIG Products
The rapidly rising prevalence of a variety of hematological and neurological disorders such as alloimmune thrombocytopenia, idiopathic thrombocytopenic purpura (ITP), and myasthenia gravis is the chief factor driving the intravenous immunoglobulin (IVIG) market. For instance, the occurrence of myasthenia gravis in the U.S. has been assessed at 14 to 20 cases out of 100,000 people, which comes to around 36,000 to 60,000 cases in the country. This neuromuscular transmission has a high probability of remaining undiagnosed and thus the prevalence of this disease is actually much higher. Over 40% of the world’s IVIG products are used to treat neurological diseases, thus the rising prevalence of neurological disorders is a highly significant factor of growth for the global IVIG market.

Moreover, the mounting global population of geriatrics, which is more vulnerable to diseases due to poor immunity, is also a key factor driving the IVIG market. According to the WHO, the global geriatric population is expected to increase from 524 mn in 2010 to 1.5 bn by 2050. This is anticipated to drive the increased demand for better immunological treatments, which in turn would provide opportunities for companies operating in the global intravenous immunoglobulin market. The steady rise in the use of intravenous immunoglobulin for the treatment of off-label indications a significant rise in the blood plasma yield across the globe are also likely to drive the intravenous immunoglobulin (IVIG) products market.

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High Cost of Treatment and Potential Side Effects to Hamper Market Growth

One of the key challenges that could hamper the overall development of the global IVIG market is the comparatively much higher cost of plasma collection and manufacturing processes as compared to conventional pharmaceutical manufacturing and processing products. Moreover, immunoglobulin products being derivatives of blood, they require highly sophisticated methods and equipment for collection, purification, and storage. This scenario adds to the overall cost and complexity of IVIG products and therapies.

Intravenous immunoglobulin (IVIG) preparations also have several related side effects, which could lead to serious health problems in some patients. Owing to this, patients are sometimes discouraged from continuing IVIG therapies. Side effects associated with the use of IVIG also sometimes encourage clinicians to opt for alternate therapies. This factor is likely to restrain the overall development of the intravenous immunoglobulin (IVIG) market in the next few years.

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This review of the market is based on a recent market research report published by Transparency Market Research, titled “Intravenous Immunoglobulin (IVIG) Market - Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2016 - 2024.”

Prepacked Chromatography Columns Market Size to Accelerate at a Rapid CAGR of 8.4% till 2024

The opportunity in the global prepacked chromatography columns market is anticipated to rise US$1.6 bn in 2015 to be worth US$3.3 bn by 2024. If these values hold true, the market is estimated to register a CAGR of 8.4% during the forecast period.
Growing Usage of Prepacked Chromatography Columns in Sample Preparation
Based on product type, the prepacked chromatography columns market is led by the >1L segment, which accounted for a share of just short of 50% in 2015. This segment is also anticipated to expand at a pace greater than the other segments, reporting a CAGR of 8.7% from 2016 to 2024. By technique, hydrophobic stationary phase chromatography held a major share in the prepacked chromatography columns market, with multimodal chromatography expanding at the fastest pace.

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On the basis of application, the sample preparation segment accounted for the leading share in the market while protein purification is forecast to report a high growth rate. Based on end use, the prepacked chromatography columns market was dominated by pharmaceutical biotechnology, and analytical laboratories are anticipated to emerge as the most lucrative end-use segment.
Geographically, North America accounted for a major share of 33.9% in the global prepacked chromatography columns market in 2015. Retaining its lead throughout the forecast period, the demand for chromatographic techniques is anticipated to rise in the region. On the other hand, Asia Pacific is poised to grow at an impressive 10.2% CAGR from 2016 to 2024.

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Wide Range of Application of Prepacked Chromatography Columns a Major Growth Driver
“Prepacked chromatography columns are well suited for various industries for the separation as well as detection of organic molecules and components,” the lead analyst notes. As a result, these columns play a significant role in the production of biopharmaceutical products. Prepacked chromatography columns are also used in industries such as biotechnology, food and beverages, agriculture, chemicals, research, and forensics. This wide range of application is a key factor boosting the global market.

“The number of monoclonal antibodies used in clinical trials and those approved for various therapeutic applications has significantly increased in recent years,” the TMR analyst states. This growing need for therapeutic monoclonal antibodies has also supported the prepacked chromatography columns market.

In contrast, the economic slowdown in several countries over the past decade has had a considerable impact on government budgets and funding when it comes to research within the healthcare sector. This has adversely impacted the global market for prepacked chromatography columns market. Moreover, the high prices of columns and limitations resulting from clogging and fouling act as deterrents to the market.

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The global market for prepacked chromatography columns market is immensely consolidated, with the top two players accounting for a 78% share in the market in 2015. Of these, GE Healthcare has been the clear leader, dominating over more than half the prepacked chromatography market that year. Repligen, on the other hand, has been gaining momentum over the years, giving its competitor a run for its money by focusing mainly on single-use or disposable manufacturing facilities.
Transparency Market Research has found that some of the smaller players have been emphasizing on strategies such as competitive pricing, offering customized products, engaging in symbiotic alliances, and expanding their product portfolio to gain a share in the global prepacked chromatography columns market. For instance, in May 2016, Agilent Technologies launched the Agilent 1260 Infinity II liquid chromatography system so as to reduce its operational costs, improve overall usability, and strengthen its position in the global market.

White Biotechnology Market; Applications across Energy Industry to Offer Favorable Returns

The rising awareness regarding the enormous benefits of the eco-friendly products manufactured through the application of white biotechnology principles has paved the way for the development of the global white biotechnology market in the past few years. Government bodies are increasingly focusing on raising awareness regarding the need for adopting greener technologies such as white biotechnology across the industrial segment. Funds allocated for increasing R&D activities in the field and instigation of strict emission regulations are compelling industries to increasingly adopt white biotechnology principles and products.

Transparency Market Research states that the global white biotechnology market will expand at a healthy CAGR of 4.5% over the period between 2016 and 2024. Rising at this pace, the market, which held an opportunity of US$178.1 bn in 2015, will reach US$262.3 bn by 2024.

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Applications across Energy Industry to Offer Favorable Returns

Application-wise, the energy segment is presently the largest contributor to the global white biotechnology market. In 2015, the segment accounted for a share of over 32% of the global market, which is expected to rise moderately by 2024. The pharmaceutical industry is the second-largest application area, accounting for a nearly 29% share in the global market in 2015. The energy segment held the most prominent position in the global white biotechnology market owing to the increased demand for bioenergy in developed economies.

The increased ease of application of white biotechnology has also made it more easily replaceable across applications that prominently used non-renewable energy sources. Additionally, the increased awareness regarding the cleaner nature of white biotechnology products have also increased their adoption across the energy industry in the past few years. Over the period between 2016 and 2024, the segment is expected to retain its dominance and expand at a healthy 4.8% CAGR.

North America to Retain Dominance but Asia Pacific to Present Most Promising Growth Opportunities

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North America is presently the largest regional market for white technology, accounting for a dominant share of over 35% of the overall market in 2015. Substantial funds provided by the government for research and development in the field and increase in demand for green products from consumers are the key factors strengthening North America’s position in the global market. In the next few years as well, the North America market for white 
biotechnology is expected to remain the largest contributor to the market’s overall revenues, chiefly owing to an increase set of applications across industries such as pharmaceuticals, food, energy, and feed.

Nevertheless, the market for white biotechnology in Asia Pacific is expected to exhibit the highest CAGR of 5% in terms of revenue contribution to the global market over the period of 2016 and 2024. The Asia Pacific market will be driven primarily by the rising demand for renewable resources across developing countries in the region. The abundance of raw materials that can be used for producing white technology products will also enable the regional market to emerge as the most promising region for investments.

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Some of the key vendors operating in the global white biotechnology market are Archer Daniels Midland Company, Novozymes, BASF SE, Cargill, Inc., DuPont, Corbion, and Lesaffre.

Biomedical Refrigerators and Freezers Market Size to Escalate at the Healthy CAGR during 2016 – 2024

The global market for biomedical refrigerators and freezers held an opportunity of US$2.91 bn in 2015. The market is expected to expand at a 4.21% CAGR over the period between 2016 and 2024, and rise to a valuation of US$4.28 bn by 2024.
Rise in Research Activities and High Demand for Blood Transfusion and Personalized Medicines to Stimulate Market’s Growth

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The demand for biomedical refrigerators and freezers has substantially increased in the past few years, primarily owing to the sustained increase in research activities in the biomedical industry. The rising prevalence of a number of infectious and chronic diseases across the globe, alarming rise in the world’s geriatric population base, and rising healthcare expenditures are pushing the development of healthcare infrastructures across the world. The increased demand for personalized medicines and a vast rise in the numbers of blood transfusions taking place across the globe have further increased the demand for reliable biomedical refrigerators and freezers on a global front.

The market has also benefitted from government initiatives the increased demand for technological upgrades in healthcare infrastructure, especially in emerging economies with flourishing medical tourism industry and a rising population of affluent consumers, in the past few years. However, the market’s development is hindered to a certain extent owing to the high cost of products and rising use of refurbished equipment.

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Demand for Environment-friendly Refrigerators and Freezers Gathers Strength

Emission of harmful greenhouse gases is a major concern with conventional refrigerators and freezing equipment. As the concerns and awareness regarding the harmful effects of these emissions to the health of the planet rise globally, the demand for greener equipment is gathering strength. In the next few years, most of the new product designs entering the global biomedical refrigerators and freezers will be greener. The switchover will be expedited by strict government regulations regarding emission control and initiatives from product manufacturers toward innovation.

Plasma Freezers and Blood Banks to Emerge as High-impact Driver

In terms of product types, the segment of plasma freezers presently dominates the global biomedical refrigerators and freezers market. The segment accounted for a share of over 28% in the global market in 2015 and is expected to retain dominance over the forecasting horizon as well, majorly owing to the rising demand for storage of fresh frozen plasma. In terms of application, the market is expected to see the highest revenue flowing in from the blood bank industry in the next few years. The market for biomedical refrigerators and freezers is expected to expand at the fastest rate in Asia Pacific through 2024, although North America will continue to account for a larger share in the market in terms of revenue contribution.

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The global biomedical refrigerators and freezers market has a handful of regional players and only a few international companies, reports Transparency Market Research (TMR) in a recent report. Though regional players command power in their respective countries, giving stiff competition to global ventures with their economical offerings, the market witnessed the dominance of three international companies in 2015 - Thermo-Fisher Scientific, Inc., Panasonic Healthcare Co., Ltd., and Eppendorf AG. Collectively, these international giants accounted for nearly 60% in the global market.
TMR analysts suggest that the global biomedical refrigerators and freezers market will amass a prominent share in overall revenues from emerging markets in the next few years. To appeal to clients and exploit the vast growth opportunities in these regions, leading vendors are being compelled to offer low-priced products and enter into collaborations with promising regional players.

Plasma Protein Therapeutics Market is expected to rise at a CAGR of 7.0% between 2016 and 2024

The use of plasma protein therapeutics has significantly increased in medical applications. This, coupled with the rising aging population, its medicinal use in novel indications, and the advent of new plasma-derived therapies, has been propelling the market for plasma protein therapeutics. Transparency Market Research (TMR) projects the market to continue exhibiting robust growth worldwide between 2016 and 2024.

Recent advancements introduced in plasma protein therapeutics aimed at improving the quality of patient care have been pivotal in fuelling their demand. These advancements have also proven crucial in guaranteeing donor’s safety. The increasing demand for immunoglobulin (IG) and the increasing use of protein therapeutics will thus augment demand for plasma protein therapeutics. TMR expects, the global market for the same to rise at a CAGR of 7.0% between 2016 and 2024. The market stood at US$18.5 bn in 2015 and is expected to reach US$31.84 bn by the end of 2024. Despite exhibiting growth at a positive rate, stringent regulations and lack of proper reimbursement policies could hamper the market’s trajectory.

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North America, trailed by Europe, Exhibits Most Lucrative Prospects for Market

Regionally, North America, Asia Pacific, Europe, Latin America, and Rest of the World constitute the most lucrative markets for plasma protein therapeutics. Among these regions, North America held the dominant share in the global market in 2015, trailed by Europe. New indications, the increasing geriatric population, and investments in novel researches are boosting prospects for the market in North America. As per TMR, the North America plasma protein therapeutics market is expected to reach US$13.8 bn by the end of 2024 from a valuation of US$7.5 bn in 2015. If the figures hold true, the regional market will exhibit a CAGR of 7.9% during the forecast period.

In Europe, demand for protein therapeutics is increasing consequent to the rise in the number of clinical indications for immunoglobulin. Since immunoglobulin finds application across hematology, neurology, dermatology, nephrology, immunology, ophthalmology, rheumatology, and others, demand for protein therapeutics in Europe is expected to remain high.

During the forecast period, TMR projects Asia Pacific to emerge as the most lucrative market for plasma protein therapeutics. The rising demand for albumin and immunoglobulin in Asia Pacific is bolstering prospects for expansion of the market in the region. Furthermore, the region is also known to import albumin and immunoglobulin from North America and Europe. China as per TMR, imports nearly half of its albumin supply in order to bridge the demand and supply gap. The albumin segment is thus expected to register the fastest growth in Asia Pacific. In Latin America, however, the plasma protein therapeutics market is restrained by low rate of diagnosis and treatment and high pricing.

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Growth to be Facilitated by Rising Incidence of Immunodeficiency Disorders
Plasma protein therapeutics is increasingly used in the treatment of primary immunodeficiency disorder (PID). The PID segment is likely to exhibit a CAGR of 7.6% between 2015 and 2024. The PID treatment segment is poised to gain considerably from the increasing investment immunoglobulin. Furthermore, with the increasing incidence of secondary immunodeficiency disorders, applications of plasma protein therapeutics is likely to increase across the treatment of prolonged illnesses. The most common secondary immunodeficiency disorders include diabetes, myeloma, HIV infection, and under-nutrition. Despite being a rare disorder, treatment of hereditary angioedema (HAE) has become possible due to the growing awareness regarding the disease worldwide. This is expected to boost the demand for plasma protein therapeutics significantly.
Some of the leading players operating in the global plasma protein therapeutics market include
Baxter International, Biotest, CSL Behring, Grifols, S.A., Kedrion, Octapharma USA, Inc., Shire plc, and China Biologics.

Friday 22 December 2017

Single-Use Bioreactors Market foreseen to grow exponentially over 2017 - 2026

Single-use bioreactors available today are robust and offers high performance which is necessary for the commercial manufacturing of biopharmaceutical products. Improvements in the bioreactor designs, film technology, sensor systems and stirring mechanisms are resulting in the increasing adoption of the single-use bioreactors. Manufacturers are also closely working with their customers to comply with the changing needs such as for next-gen gene and cell therapies, and for continuous bioprocessing. New generation single-use bioreactors are being designed while keeping in mind the processes and final drug product perspectives by the end users.

Recent developments in single-use bioreactors by manufacturers are focused on improving mixing, reducing complexity, and avoid leakage and integrity issues. Improvements in the cell-culture processes are also leading to the rise in adoption of single-use bioreactors.

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Some of the key market players in the report are Sartorius Merck Millipore, Stedim Biotech, GE Healthcare, Thermo Fisher Scientific, Danaher, Parker Hannifin, Eppendorf, Applikon Biotechnology, Cesco Bioengineering, Celltainer Biotech, Cellexus, PBS Biotech, Distek, Pierre Guerin, and Solida Biotech.

Global Single-Use Bioreactors Market to Witness Strong Growth during the Forecast Period 2017-2026

According to the latest report compiled by Transparency Market Research (TMR), the global single-use bioreactors market is expected to witness robust growth. It is also estimated to increase to 13.5% CAGR throughout the forecast period 2017-2026. The market is also projected to reach US$ 1,547.3 million revenue by 2026 end.

The global single-use bioreactors market is segmented on the basis of product type, cells type, end user and molecule type. Based on the product type, the segmentation consists of media bags, single use bioreactor systems and filtration assemblies. Among these, single use bioreactor systems are anticipated to witness significant growth throughout the forecast period. Based on the cells type, the market is categorized into bacterial cells, mammalian cells, yeast cells, and others. Between 2017 and 2026, mammalian cells are expected to witness the highest growth.

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By end user, biopharmaceutical companies are anticipated to emerge as the largest users of the single-use bioreactors during 2017-2026. In the terms of molecule type, the segment includes gene-modified cells, stem cells, vaccines, monoclonal antibodies (MABS) and others. Among aforementioned molecule types, monoclonal antibodies (MABS) is likely to witness strong growth in the global single-use bioreactors market between 2017 and 2026.

Europe to Emerge as the Most Lucrative Market in the Global Single-Use Bioreactors Market
Europe is anticipated to be the most dominating region in the global single-use bioreactors market during 2017-2026. Owing to the presence of some of the world’s leading pharmaceutical companies in Europe, the region is likely to witness growth. The region is expected to account for the largest share, due to the patient cliff of many biologics drugs in the region and the strong support by the government to the biopharmaceutical companies in order to establish new therapies in biologics. Also, the increasing use of single-use bioreactors in cell culture-based manufacturing is driving the demand in the region. Single-use bioreactors are also becoming technologically advanced and are also being provided at competitive cost.

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Meanwhile, North America and APEJ are also likely to witness growth in the single-use bioreactors market. Increasing investment by biopharmaceutical companies to establish their manufacturing facilities is driving the growth in APEJ. Increasing focus on research activities and well-established healthcare industry is resulting in the growth of the market in North America.

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Carbon Dioxide Incubators Market foreseen to grow exponentially over 2017 - 2026

A new report composed by Transparency Market Research (TMR) provides insights and analysis on the global carbon dioxide incubators market for the forecast period - 2017 to 2026. The report has profiled prominent players actively contributing to the market growth, and has tracked their occupancy using an intensity map. Key market players identified by the report include Shanghai Boxun Medical Biological Instrument Corp., LEEC Limited, Bellco Glass, Inc., Memmert GmbH + Co. KG, BINDER GmbH, Sheldon Manufacturing, Inc., Eppendorf AG, Panasonic Healthcare Co., Ltd., and Thermo Fisher Scientific Inc.

Presence of numerous vendors has made the global carbon dioxide incubators market’s nature to be fragmented, albeit product offerings of these vendors are similar to an extent in terms of design and functionality. The market is less competitive on the back of slow technology upgradation cycle regarding carbon dioxide incubators. Global leading vendors of carbon dioxide incubators are adopting after sales services and streamlined distribution systems for retaining their dominance in the market.

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Increasing Technological Penetration in Production of Carbon Dioxide Incubators – Key Growth Driver

Global market for carbon dioxide incubators is projected to register a splendid expansion through 2026. Worldwide sales of carbon dioxide incubators are estimated to account for roughly US$ 300 Mn revenues by 2026-end. Increasing technological penetration in the production of carbon dioxide incubators is considered to be one of the key growth drivers for the market. A great example for this is the introduction of an advanced version of carbon dioxide incubator equipped with HEPA filters and infrared radiation control, which offers results with enhanced quality. With laboratories taking efforts toward incorporating automation, demand for carbon dioxide incubators will witness a consistent rise in the near future. Future of the market for carbon dioxide incubators is centered upon upgradation to newer application-specific products equipped with more sophisticated features.
However, high prices of carbon dioxide incubators are expected to remain a major factor restraining their adoption. Customization requirements based on working environment which include additional shelves & trays, or add-on accessories, along with their service, maintenance, and repair further add to the cost of these incubators. Market players emphasizing on development of technologically sound and cost-effective carbon dioxide incubators for high quality outputs are likely to witness lucrative growth opportunities in the foreseeable future.

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North America to Remain Largest Market for Carbon Dioxide Incubators

In terms of revenues, North America is likely to remain the largest contributor to growth of the global carbon dioxide incubators market, followed by Europe. Revenues from the markets in North America and Europe are collectively projected to account for over half share of the market by 2026-end. Asia-Pacific excluding Japan (APEJ) is projected to register a double-digit CAGR through 2026, and is anticipated to remain the fastest expanding market for carbon dioxide incubators, followed by North America.

On the basis of product type, water jacketed carbon dioxide incubators will continue to be sought-after among end-users, with sales poised to account for nearly US$ 200 Mn by 2026-end. Revenue share of water jacketed carbon dioxide incubators in the market will remain considerably higher than combined revenue share of air jacketed and direct heat carbon dioxide incubators.

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Above 200L Capacity of Carbon Dioxide Incubators to Remain Preferred

Carbon dioxide incubators with capacity of above 200L will remain preferred in the market. However, sales of carbon dioxide incubators with capacity of above 100L & below 200L are projected to register the fastest expansion in the market through 2026. In addition, revenues from sales of carbon dioxide incubators having below 100L capacity are expected to remain sluggish during the forecast period.

Although laboratory research and clinical applications of carbon dioxide incubators are expected to remain the most financially rewarding, in vitro fertilization application of these incubators will register a relatively higher CAGR through 2026. However, revenues from the former will remain significantly larger than the latter throughout the forecast period.

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Membrane Separation Systems Market foreseen to grow exponentially over 2017 - 2025

Amidst a fragmented vendor landscape in the global membrane separation systems market, large players that operate globally have been observed to hold supremacy in the overall market, as per one of the current reports by Transparency Market Research (TMR). In a typical scenario in this market, small scale vendors operate in regional markets serving a few end-use industries, whereas market leaders such as The Dow Chemical Company and Koch Membrane Systems Inc. not only operate globally but have serve a number of end-use industries. The topnotch companies are also upping spends on research and development to introduce innovative systems.

Pall Corporation, Sartorius AG, 3M, Amazon Filters, Advantec MFS Inc., GE Healthcare, Merck Millipore, Novasep, and TriSep Corporation (Microdyn-Nadir US, Inc.) are to name some other prominent companies in the global membrane separation systems market.

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As per estimates of a report by Transparency Market Research (TMR), the global membrane separation systems market will clock a CAGR of 9.3% for the forecast period from 2017 to 2025. Expanding at this rate, the market’s valuation of US$28,134.4 mn in 2016 will become US$61,801.9 mn by the end of 2025.

The microfiltration segment, among the key technology segments, held the leading share in the global membrane separation systems market in 2016. By application, the environmental segment holds the leading share among other segments in the membrane separation systems market. Europe held the commanding share vis-à-vis revenue in the global membrane separation systems market among other key regions in 2016.

Measures to Save Water and Interest for Wastewater Treatment Stokes Demand

Amongst several driving factors, a significant part of the demand for membrane separation systems originates from municipal corporations. At present, measures for water reuse and wastewater treatment to save wastage of the essential commodity is the consideration of environmental agencies. This has boosted the uptake of membrane separation technologies, which in turn is stoking demand for membrane separation systems.

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In particular, emerging economies that are underway rapid industrialization and facing population explosion in water-stressed areas are expected to augment the growth of this market in the upcoming years.

Membrane separation technology has emerged as the most important separation technology over the last couple of years. This is because membrane separation technology is free of chemicals, consumes less energy, and operates in an organized manner, which conventional separation techniques lack. Due to the distinct offerings of membrane separation technology, it is increasingly being used for different processes in water management, wastewater and process water treatment, food and beverage, life sciences, and pharmaceutical industries. The technology is also used for separation processes in chemical, petrochemical, and manufacturing industries.

Apart from this, several governments and metropolitan planners are awakening to the impact in the event of a shortage of water which is an everyday essentiality. This is pushing the need for innovations for water treatment, thereby paving way for the growth of the worldwide market for membrane separation systems.

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High Set-up and Operational Costs Crimps Growth

However, on the downside, high establishment and operational costs, insufficient infrastructure, and availability of other water cleaning and treatment procedures are posing a challenge to the growth of membrane separation systems market.
The information presented here is based on the findings of a TMR report, titled “Membrane Separation Systems Market (Technology – Microfiltration, Ultrafiltration, Nanofiltration, Reverse Osmosis, Chromatography, and Ion Exchange; Application – Environmental, Food & Beverages, and Healthcare; Material – Polyethersulfone, Polysulfone, Cellulose Based, Nylon, Polypropylene, Polyvinylidene Fluoride, Polytetrafluoroethylene, Polyacrilonitrile, and Polyvinyl Chloride) – Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 2017–2025.”

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