Laser Capture Microdissection Market: Overview
Laser capture microdissection (LCM) technology is a contamination free procedure for obtaining subpopulations of tissue cells under direct microscopic visualization. Furthermore, laser-capture microdissection technology isolates specific cells by dissecting unwanted cells. Laser capture microdissection technology harvests the cells of interest directly to give pure enriched cells. This technology helps in preserving the genuine morphology of the dissected cell or tissue sample. The laser capture microdissection technology by type can be segmented into software, instruments, consumables, and services. Furthermore, the market for laser capture microdissection by system can be segmented into infrared LCM, ultraviolet LCM and Immunofluorescence LCM. In addition, by end users the laser capture microdissection market can be segmented into biotechnology and pharmaceutical companies, hospitals and government research institutes among others. Moreover, by application the market can be segmented into research and development and diagnostics among others.
The laser capture microdissection market by geography has been segmented into Europe, Asia Pacific, North America and Rest of the World (RoW).
Laser Capture Microdissection Market: Trends and Opportunities
Increasing expenditure on healthcare along with technological advancement in the field of healthcare is one of the major driving factors for the laser capture microdissection market. Furthermore, increasing information regarding the technical advantages obtained from laser-capture microdissection techniques is fueling the market at the global level. In addition, growing funding and expenditure on research and development activities of companies involved in this market is stimulating the growth of this market. High maintenance and manufacturing cost of accessories and equipment along with lack of expertise professionals in this field is some of the restraining factors which may hinder the growth of this market.
Research and development and diagnostics among others are major application areas of laser-capture microdissection technology. Furthermore, government research institutes and hospitals are major end users of this technology. Moreover, ultraviolet LCM and infrared LCM are leading the market globally. Increasing preference of laser-capture microdissection technology in forensic science and molecular biology under the research and development application segment is one of the major driving factors for the market.
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Laser Capture Microdissection Market: Geographical and Competitive Dynamics
With the increasing technological advancement and growing application of laser-capture microdissection (LCM) technology in pharmaceuticals, hospitals and research and development institutes are fueling the market globally. North America dominated the market for laser-capture microdissection in 2014 and is expected to maintain its position over the forecast period 2015 to 2023. U.S. is the major market across North America. Moreover, with the increasing expenditure on research and development activities of companies dealing in this market along with increasing awareness regarding the technological advancement is driving the market for laser-capture microdissection across Asia Pacific. China, Japan, India, contributes in the positive growth of this market across Asia Pacific. Growing application areas of this technology in the fields such as forensic science, diagnostics and molecular biology are having a positive impact on the growing market for laser-capture microdissection in Rest of the World (RoW).
Some of the key players operating in the laser capture microdissection market are Carl Zeiss AG (Germany), Molecular Machines & Industries (Germany), Ocimum Biosolutions LLC (U.S.), DeNova Sciences Pte. Ltd. (Singapore), Danaher Corporation (U.S.), Thermo Fisher Scientific, Inc. (U.S.), Indivumed GmbH (Germany), AvanSci Bio, L.L.C. (U.S.), Theranostics Health, Inc.(U.S.) and 3DHISTECH Ltd. (Hungary) among others.
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Human tissues are composed of complex mixtures of different cell types and their biological analysis requires the procurement of pure samples of the cells of interest. Number of approaches have been used in attempts to overcome this difficulty. Laser capture microdissection (LCM) is anautomated sample preparation technology used to isolate and harvest the specific cells of interest from tissue, or organisms by direct microscopic visualization. The technique also called as laser microdissection (LMD), or laser assisted microdissection (LAM or LMD). This technology facilitates the formulation of homogenous isolates of clear cells through which DNA/RNA and various proteins can be achieved for further performingmass spectrophotometry, western blot analyses, polymerase chain reaction (PCR), and quantitative PCR. Certain benefits, such as contamination free and contact free technique, allows more efficient and accurate results, and preservance of cells with an original morphology are expected to provide good growth in the global market. Laser microdissection is now used in a large number of research fields, e.g. cancer research,neurology, forensics or climate research,and plant analysis. The method is for the time being also applied for manipulation of cell cultures or for microengraving of coverslips.A diversity of downstream applications of laser capture microdissection technique are exist includes DNA genotyping and loss-of-heterozygosity (LOH) analysis, RNA transcript profiling, proteomics discovery, cDNA library generation, and signal-pathway profiling.