Small Bone and Joint Orthopedic Devices Market - Some Predictions for Next Few Years

The growing prevalence of degenerative disorders, such as osteoarthritis and osteoporosis, has been fuelling the demand for small bone and joint orthopedic devices significantly across the world. In 2014, the global opportunity in these devices was worth US$4.1 bn. Expanding at a CAGR of 8.10% during the period from 2015 to 2023, it is likely to reach US$8.2 bn by the end of 2023.

The rising demand for radial head repair devices and three-piece mobile ankle arthroplasty and the growing popularity of shoulder arthroplasty devices are likely to drive the market’s growth in the coming years.

North America to Remain Key Contributor to Small Bone and Joint Orthopedic Devices Market

Based on region, the worldwide market for small bone and joint orthopedic devices has been segmented into Europe, North America, Latin America, Asia Pacific, and the Middle East and Africa. Among these, North America occupied the leading position in 2014 with a share of 46.9%.

The increasing number of orthopedic procedures, the rise in the obese population, and continual introduction of technically advanced products has boosted the sale of these devices in this region over the recent past. Although the future of these devices looks good in this region, its market share, however, is likely to decline a little over the forecast period, reaching 46.5% by 2023. Despite the decline, North America will remain the key contributor to the overall market in the coming years, states TMR.

Asia Pacific, on the other hand, is projected to present the most lucrative opportunities for small bone and joint orthopedic devices in the near future on account of the improving economy of several Asian countries, which is anticipated to boost the healthcare infrastructure in the region. Apart from this, the increasing disposable income of people in this region has enabled them to afford expensive treatments, which is also expected to act as a key driving force behind the growing demand for these devices in Asia Pacific over the years.

The opportunity in small bone and joint orthopedic devices in North America is estimated to reach US$3.8 bn by 2023, whereas Asia Pacific is projected to register the fastest CAGR of 8.40% between 2015 and 2023.

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Demand for Small Bone and Joint Orthopedic Devices to Remain High in Shoulder Reconstruction

Shoulder reconstruction reports the most prominent demand for small bone and joint orthopedic devices across the world. The increasing shift of preferences from partial and resurfacing shoulder implants to reversed shoulder implants among patients suffering from large rotator cuff tears has emerged as the primary factor that has fueled the application of these devices in shoulder reconstruction. Along with this, the rising usage of stemless shoulder implants for the treatment of young patients is also stimulating the demand for these devices in this segment. The opportunity for small bone and joint orthopedic devices in shoulder reconstruction is expected to expand to US$4.7 bn by 2023.

The leading manufacturers of small bone and joint orthopedic devices across the world are Flower Orthopedics, Z-Medical GmbH + Co. KG, Arthrex Inc., Tecomet Inc., Wright Medical Group N.V., F. Hoffmann-La Roche Ltd., Depuy Synthes, Smith & Nephew plc, Stryker Corp., Zimmer Biomet Holdings Inc., Acumed LLC, and DJO Global.

Growing Number of Heart Failure Incidences to Augment Demand for Dilated Cardiomyopathy Medications

Dilated cardiomyopathy has led to an increase in heart failures worldwide among adults and children also giving rise to need for heart transplant. Dilated cardiomyopathy can develop between the ages of 20 and 40 years, genetic inheritance being the most common factor affecting 30%-40% of the DCM patients globally. Due to the increasing cases of heart failures, the demand for dilated cardiomyopathy drugs is expected to increase as the need for blockbuster drugs in developed countries is becoming evident.

According to a report published by Transparency Market Research, the global dilated cardiomyopathy therapeutics market is expected to witness a negative CAGR of -7% from 2014 to 2020. The global dilated cardiomyopathy market was valued at US$651 mn in 2013 and is projected to decrease to US$328.6 mn by 2020.

How can an increase in heart failure cases help drug manufacturers to develop innovative and advanced therapeutics?

According to a study, in every one million children across the globe, six are diagnosed with dilated cardiomyopathy. It is found commonly among children who are under the age of 2 years. There has also been a substantial increase in the number of heart failures among adults as well, leading to a global rise in the demand for dilated cardiomyopathy therapeutics. Of the overall congestive heart failures that occur each year, DCM comprises 30%-40%. Due to this, several leading companies have introduced clinical trials and invested for the development of therapeutics for dilated cardiomyopathy.

For instance, Cincinnati Children’s Heart Institute announced a breakthrough development on 19 May, 2016 where genetically inherited heart diseases can be diagnosed and treated with the help of biomechanics and stem cells. Similar breakthroughs are underway in the field of dilated cardiomyopathy drugs to help in the growth of the market with better techniques and medications.

What factors are responsible for the negative growth of the dilated cardiomyopathy therapeutics market?

DCM drugs segment has no drug that has been approved by FDA till date. The drugs used for the treatment of dilated cardiomyopathy and congestive heart failure are same and have no distinct formulation. DCM drugs are reported to have side effects and this has thus affected revenues from DCM therapeutics substantially. The use of devices and gene therapy that provide enhanced relief without any side effect has highly restrained the dilated cardiomyopathy therapeutics market growth globally.

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However, companies in the DCM drug market along with research organizations are working on the approval of aldosterone antagonists combined with ARBs or ACE. It is expected that these drugs will play a positive role in reducing the progress of Duchenne muscular dystrophy. This approval will help in the acceleration of sales of DCM drugs as aldosterone antagonists are one of the main additives in the formulation of DCM medications.

The increase in genericization activities of DCM drugs will also provide manufacturers with opportunities to improve their product position in the global market and also witness a positive growth of the DCM drugs market.

North America dominated the DCM drugs market in 2013 due to the demand for branded drugs and increasing heart failure cases. Asia Pacific is projected to be the fastest growing market for DCM followed by the Rest of the World owing to the per capita income increase, and improving economic standards in the region. Some of the key players operating in the global DCM drugs market are Celladon Corporation, Novartis International AG, Vericel Corporation, Sanofi S.A., AstraZeneca plc, and GlaxoSmithKilne plc.

Weight Loss Stomach Pump Market - Latest Trends & Insights 2024

Weight loss stomach pump is a device which provides effective control over the calorie absorption by the body. It is an external pump that spill of stomach contents into the toilet. The device is a minimally invasive which includes a tube that goes inside the stomach to port outside. The device is used to lose weight easily than people who use to have controlled diets, surgery or batch of devices to make the stomach smaller. Patients need to be regularly monitored by the health care provider and should be guided by a diet consultant in order to reduce their calorie intake. As per the clinical trials reports, the average patient observe a loss in 46 pounds in the first year and 50 pounds in the following year.

Weight loss stomach pumps are usually utilized by bulimia or assisted bulimia patients of an age 22 or more. Weight loss stomach pump usage are expected to grow at a high rate owing to increase in a patient with more obesity problem and bypass gastric surgery. Weight loss stomach pump market is expected to grow at a significant CAGR due to their ability to lose the weight of the body with minimum invasiveness. Moreover, an increase in obesity and bulimia patients, fewer side effects, develop in life style habits, and increase in non-surgical treatment worldwide will also support the market growth. However, side effects associated with surgery are certain challenges which may hamper the market of weight loss stomach pump.

The weight loss stomach pump market has been segmented by disease type, by end-user, and by geography. In terms of disease type, the weight loss stomach pump market has been categorized into anorexia, bulimia, and diabetes. Unhealthy lifestyle is influencing in increasing obesity associated diseases among healthy habitat. Hence, weight loss stomach pump would play a major part in an effectively control over obesity. The end-users for the market include hospitals, nursing homes, clinics, and others. The weight loss stomach pump provider’s offer specialized programs to the end-users assisting in management of health plans by offering solutions to increasing costs of complexities during treatment.

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Geographically, weight loss stomach pump market is segmented into two major regions: North America, and Europe. North America was observed to be the largest weight loss stomach pump market due to extensive technological advancements in the region. Countries such as the U.S. and Canada have been successful in implementing weight loss stomach pump in their healthcare system, which as a result would boost the market growth. Moreover, the presence of other developed healthcare infrastructure, promising government initiatives in executing weight loss stomach pump in the current healthcare infrastructure, and constantly improving reimbursement scenario would further propel the market growth. Europe was observed to be the second largest market in the weight loss stomach pump owing to enhanced weight loss therapy in the healthcare processes and implementation of stomach pump, a weight loss device in the region.

In June 2016, the U.S. Food and Drug Administration approved a new obesity treatment devices such as Aspire Assist System which is applicable on patients who are moderately overweight. The FDA reviewed results from a clinical trial of 111 patients treated with AspireAssist and appropriate lifestyle therapy. In August 2015, the ORBERA Intragastric Balloon System is a weight-loss system, which uses a gastric balloon that occupies space in the stomach to help patients lose weight. Patients with ORBERA lost an average of 21.8 pounds (10.2% of their body weight) after the device had been in place for six months. The major players operating in this market include Apollo Endosurgery, Inc.( ORBERA® balloon), Aspire Bariatrics, Inc.( AspireAssist System), among other significant players worldwide.

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Surgical Robots: Highest Share in the Overall Medical Robotic Systems Market

A new Transparency Market Research report states that the global medical robotic systems market was valued at US$5.48 bn in 2011 and is predicted to reach US$13.6 bn in 2018. It is expected to expand at a healthy CAGR of 12.60% from 2012 to 2018. The title of the report is “Medical Robotic Systems Market - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2012 - 2018”.

According to the report, the medical robotic systems market is majorly fuelled by the enhancement of automation technologies, rising baby boomer population, and the rising incidence of disabilities in human beings that impede their day-to-day physical motions. Furthermore, the absence of skilled medical personnel, the soaring cost of human workers, and rising healthcare costs have raised the inclination of hospitals for automating their operations and adopting methods of lean hospital management. This trend has raised the demand for medical robotic systems all around the world. On the other hand, the soaring purchase and installation costs of medical robotic systems may impede their demand in the coming years, especially in emerging economies.

On the basis of segment, the market is segmented into surgical robots, non-invasive radiosurgery, emergency response, non-medical, assistive and rehabilitation, and prosthetics robotic systems. Amongst these robotic systems, surgical robots led the market in terms of revenue. The da Vinci surgical robot and the Telelap ALF-X surgical robots are amongst the top surgical robots dominating the market. The segment of surgical robots has been further segmented into neurosurgery robotic systems, orthopedic robotic systems, noncatheter percutaneous robotic systems, steerable robotic catheters, and general laparoscopy robotic systems. The segment of noninvasive radiosurgery robotic systems is further segmented into TrueBeam STx radiosurgery system, Gamma Knife Perfexion radiosurgery system, and CyberKnife Robotic radiosurgery system.

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Moving further, the segment of emergency response robotic systems is further segmented into LS 1 - robotic system, AutoPulse Plus robotic system, and others. The segment of prosthetics has been further segmented into C-leg - knee prosthetic, Rheo – knee prosthetic, ReWalk – walking assistance exoskeleton, and i-limb ultrahand – hand prosthetic. Furthermore, the segment of assistive and rehabilitation systems has been further segmented into LARM, a robotic arm, Handy 1 assistive Robot, Lokomat, and Myomo mobility system, a muscle re-education device. The segment of non-medical robotics is further segmented into cart transportation robots, robotic hospital pharmacy, and telemedicine robots.

On the basis of geography, the medical robotic systems market is segmented into Europe, North America, Asia Pacific, and Rest of the World (RoW). Amongst these, North America held the largest share in the market in 2011 and is trailed by Europe. On the other hand, the expanding economies in Africa, the Middle East, and Asia Pacific have experienced exceptional development in healthcare infrastructure and thereby the demand for medical robotic systems in these regions is poised to rise in the forthcoming future.

Intuitive Surgical, Inc., Accuray, Inc., Hansen Medical, Inc., Titan Medical, Inc., Irobot Corporation, MAKO Surgical Corp., Stereotaxis, Inc., Varian Medical Systems, ZOLL Medical Corp., and McKesson Corporation, among others, are the prominent players operating in the market.

Continued Research Makes Biotherapeutics Cell Line Development Market a Highly Attractive Space

Over the past few years, the demand for biotherapeutics has witnessed a significant rise, thanks to the increasing prevalence of chronic diseases such as diabetes, rheumatoid arthritis, cancer, and multiple sclerosis. This growth in the demand for biotherapeutics, together with the imminent launch of several biopharmaceutical drugs, has created a substantial demand for cell line development.

On the other hand, the strict rules and policies, regulating cell culture procedures in the production of biotherapeutics are creating difficulties for participants in their business expansion. However, unmet medical needs in emerging economies of Asia Pacific, Latin America, and Africa, is expected to provide lucrative opportunities for market players over the next few years.

The global market for is estimated to with the opportunity in biotherapeutics cell line development will rise from US$56 mn in 2014 to nearly US$100 mn by 2022, rising at a CAGR of 7.50% between 2015 and 2022.

Asia Pacific to Provide Potential Opportunities for Cell Line Development in Biotherapeutics

North America has acquired the leading position in the worldwide market for biotherapeutics cell line development. In 2014, the opportunity in this region stood at US$23.5 mn, which is likely to increase to US$41 mn by the end of 2022. The presence of a large pool of leading biopharmaceutical companies has stimulated the biotherapeutics cell line development activities in this region, leading to remarkable growth in the market. The increasing base of geriatric population in this region is also presenting huge opportunities for the development of cell lines in biotherapeutics.

Europe, which emerged second in this market in 2014, is expected to report steady growth in the near future, thanks to the rising demand for biotherapeutics. The future of cell line development in biotherapeutics, however, lies in Asia Pacific, which stood at third position in 2014. The potential that this region holds can be understood by the fact that Asia Pacific is expected to register the fastest CAGR of 9.40% during the forecast period. The unmet medical needs and the increasing investments by major pharma companies is projected to amplify the development of biotherapeutics cell line in this region.

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Transfection and Selection to Report Higher Growth Rate in Near Future

Single cell cloning and transfection and selection are the two main processes for biotherapeutics cell line development. Single cell cloning led the market with a share of 96% in 2014. The growing adoption of instruments such as FACS and ClonePix has added significantly to the growth of single cell cloning in the recent times.

Although the single cell cloning segment is likely to remain leading throughout the forecast period; the transfection and selection segment with register a higher growth rate in the coming years, owing to the increase in the demand for monoclonal antibodies.

The top two players in the global biotherapeutics cell line development market are Becton Dickinson and Co. and Beckman Coulter. Boehringer Ingelheim Pharma GmbH & Co KG., CMC Biologics, Catalent Inc., Lonza Group Ltd., ProBioGen AG, Partec, SAFC, Sony Biotechnology Inc., Selexis SA, and Thermo Fisher Scientific Inc. are some of the other prominent market participants.

Radiofrequency Ablation Devices for Pain Management Market size and Key Trends in terms of volume and value 2015-2023

Radiofrequency (RF) ablation is a minimally invasive surgical procedure that involves a local anesthetic and mild sedation. This procedure is primarily used to reduce chronic low-back and neck pain caused due to degeneration of joints (due to arthritis and other spinal conditions). The procedure involves heating a small area of nervous tissue under controlled temperature. This results in blockage of pain signals transmitting from that area, thereby relieving the patient from chronic pain. The global RF ablation devices for pain management market was valued at US$ 358.7 Mn in 2014 and is projected to reach US$ 1,087.9 Mn by 2023 at a CAGR of 12.9% during the forecast from 2015 to 2023. The global radiofrequency ablation devices for pain management market has been broadly segmented on the basis of product type (capital equipment, reusables, and disposables) and geography (North America, Europe, Asia Pacific, Latin America, and Rest of the World).

Over the years, several techniques have been used to selectively destroy nervous tissue in the spinal axis, brain, and other locations in the body. However, the radiofrequency ablation devices have been proven to be the most effective and widely adopted technique to achieve pain relief for longer durations. The revolutionary changes in technology are being reflected through products such as cooled radiofrequency technology platforms which allow creation of larger lesions without excessive heating at the electrode. For instance, COOLIEF Cooled RF System from Halyard Health, Inc. (formerly Kimberly-Clark Health Care) can be used for pain management of hip, knee, cervical, thoracic, sacroiliac, transdiscal, and lumbar pain.

The global radiofrequency ablation devices for pain management market have been categorized into three segments based on type: capital equipment, reusables, and disposables. The capital equipment, i.e., RF generators are utilized to provide heat energy to destroy selective nerves carrying pain impulses from the affected organ. Products in the reusables and disposables segment are priced less in terms of US$, but garner substantial revenue in the global RF ablation devices for pain management market owing to high volume sales. These products are initially provided as part of ablation device package, but can be procured separately.

Geographically, North America held the largest share in the global radiofrequency ablation devices for pain management market in 2014, while Europe was the second largest regional market. One of the major factors responsible for the continued growth in these markets include aging population more susceptible to arthritis. According to a report by the World Health Organization, growth rate of aging population is expected to be higher in developed nations, especially in the U.S., Japan, and several countries in Europe. Hence, the market for RF ablation devices for pain management in North America and Europe will continue to progress at a healthy growth rate during the forecast period from 2015 to 2023.

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Asia Pacific will be the growth driver for global radiofrequency ablation devices for pain management market in the near future. According to the World Bank, India is likely to record the strongest economic recovery among other major developing nations from 2013 to 2016. The country is expected to witness a growth rate of 7.1% in 2016, up 2.3% from 4.8% recorded in 2013. China’s economic growth has been more than 7.5% during 2013 and is expected to continue at a similar rate in future as well. This economic growth is expected to increase the disposable income of the patient population and in turn increase the health care expenditure on novel therapies such as radiofrequency ablation devices. The rapidly aging population in Japan is also likely to contribute to the growth of the market in the region during the forecast period from 2015 to 2023.

Laboratory Thermometers Market: Regional markets, technology developments, types, applications, and the competitive landscape

Laboratory Thermometers Market: Overview

A thermometer is a device which is utilized in the measurement of temperature or temperature gradient of a body or a medium that finds its use in a wide number of applications, such as, scientific research, medicine, study of weather and various control and regulatory processes. Laboratory (lab) thermometers perform temperature measurement at a very high degree of precision, and include a variety of thermometers that find their specific usage in different laboratory applications.

Laboratory thermometers are typically utilized in scientific and research applications, which includes maintenance of a sterile work environment, monitoring of experiments, calibrating laboratory instruments and testing materials. Some of the major types of laboratory thermometers that available on the market, include, dial thermometers, glass thermometers, infrared thermometers, digital thermometers and vaccine thermometers among others. These laboratory thermometers are available in different sizes, types and a wide temperature range to satisfy the needs of the customers globally.

Laboratory Thermometers Market: Growth Enablers

Key driving factors for the growth of the global laboratory thermometers market include increasing use of laboratory thermometers in ever increasing number of research laboratories, academic institutions and other research based industries and rising demand for technologically advanced lab thermometers.

At present, many global as well as local manufacturers are providing a wide range of laboratory thermometers that are portable, maintenance free, easy to use and produce accurate results. A wide range of laboratory thermometers are used in different processes in a research lab or an industry. For instance, dial type of thermometers are majorly used in the monitoring of temperature of asphalt, concrete, soil or any other material that are used in a laboratory. Technological advancement along with growing awareness and demand for advanced lab thermometers especially in the emerging economies of the world would further boost the growth of this market.

Laboratory Thermometers Market: Region-wise Insight

Geographically, North America dominates the laboratory thermometers market followed by Europe. Key factor driving the growth of the laboratory thermometers market in these regions include vast usage of laboratory thermometers in ever increasing number of research and development activities in these regions. The heightened use of the laboratory thermometers in various other industries due to the well-established infrastructure especially healthcare and manufacturing industries in these regions are also contributing towards the growth of this market in these regions.

However, Asia Pacific is expected to be the most lucrative market for laboratory thermometers in future due to range of driving factors. Some of the key driving factors for the rapid growth of this market in the region include, increasing number of research and development activities, presence of a large number of developing economies, improving infrastructure especially healthcare and other manufacturing industries in the region. Improving healthcare infrastructure along with rising disposable income and awareness of the people in the region would contribute towards the growing demand for advanced lab thermometers. Rising number of research and development activities along with setting up of new manufacturing units in the region would increasingly utilize various laboratory thermometers, hence will contribute towards the growth of this market in the region.

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Laboratory Thermometers Market: Key Players

Some of the major players that are operating in the global lab thermometers market include Amarell GmbH & Co. KG, B+B Thermo-Technik GmbH, Brannan, Camlab, Carolina Biological Supply Company, Elektron Technology, Glas-Col, LLC, OMEGA Engineering, Inc., Physitemp Instruments, Inc., Streck, Inc., The Lab Depot, Inc., Thermo Fisher Scientific, Inc. and ThermoProbe, Inc.

The report offers a comprehensive evaluation of the market. It does so via in-depth insights, understanding market evolution by tracking historical developments, and analyzing the present scenario and future projections based on optimistic and likely scenarios. Each research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology developments, types, applications, and the competitive landscape.